Barely Significant
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The Combined Assessment of CTC and <i>ESR1</i> Status in Liquid Biopsy Samples Enhances the Clinical Value of Prediction in Metastatic Breast Cancer.

Int J Mol Sci · 2025 · PMC11900918 · PMID 40076662

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on the borderline of significanceno p-value reported
However, our results on the impact of cfDNA mutations were on the borderline of significance ( ESR1 ) or insignificant ( PIK3CA ) in Kaplan–Meier survival analysis.

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borderline significanceno p-value reported
The borderline significance of our analysis may result from the relative heterogeneity of our group of patients in terms of the observation period, so in some patients, resistance-conferring mutations may not be present because there was not enough time for the evolution of the resistance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.