Synthetic microbial consortia for the treatment of Clostridioides difficile infection in mice model.

butyricum showed an increasing trend in their proportions.

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Conversely, in the CDI group, the cecum was severely damaged, with a completely damaged mucus layer, the presence of obvious broken tissue and a fairly significant neutrophil infiltration, whilst the colon showed epithelial cell loss, mucus layer damage, and local neutrophil infiltration.

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Weight change is an important indicator of the severity of CDI and one can visually determine the course of the disease from it; however in our study, there were no significant differences between the CDI group and the B10 group, and the two groups maintained a decreasing trend until the end of the experiment (Figure 4B ).

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