Combination CD200R/PD-1 blockade in a humanised mouse model.

Immunother Adv · 2023 · PMC10112683 · PMID 37082107

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a clear trendno p-value reported

Importantly, anti-PD-1 monotherapy produced a clear trend towards reduced M2 macrophages overall, while failing to reach significance when compared to MOPC21 ( P = 0.0654).

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a slight trendno p-value reported

In both experiments, however, there was a slight trend towards more complete responses and therefore increased overall survival of mice treated with both antibodies.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.