As the volumetric difference in the ACC was trending towards significance, we included it as a covariate when comparing group differences of V T and did not find a significant effect (F 2,21 = 3.10, p = 0.07). fMRI analysis Working memory-related neural activation (defined as contrast of 1- & 2-back minus 0-back contrast) in both controls and patients can be seen in Fig. 2 B and C respectively, with activation patterns seen in both groups, including the prefrontal and cingulate cortices.
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The OMP service was reduced during the COVID-19 pandemic, restricting clinical activities to essential work only, negatively impacting numbers of patients that received both baseline and end-of-course tests, which fell from 63% to 43% (p=0.62) in month 6 and from 67% to 14% (p=0.057) in month 8 trending towards significance in the latter approaching the winter months but also coinciding with reduced OMP staff.
Significance was defined as p <.05 following Bonferroni multiple comparisons correction, while 0.05 ≤ p ≤.1 were considered trending towards significance.
While differences in emergent status of the case and need for post-operative ERCP between the four and three-port RC techniques trending towards significance, no other statistically significant differences were noted between the groups (Table 3 ).
However, the statistical difference between the control group and the TGF + DGBP + GGPP group did not reach significance ( p = 0.16) due to one outlier type value (0.35, 1.60, 1.67 and 1.39), but trending towards significance.
Trending towards significance (OR = 1.29) was a sex effect, with more males being seropositive, although the relevance of this is unknown.
CD38 had an insignificant log 2 FC of -0.53 in cryopreserved cells ( N =6, n =3, P =0.24) and −0.48 ( N =6, n =3, P =0.069) in the newly generated cell line; however, we do not believe that this is necessarily a reason to completely disregard the involvement of CD38 in the altered APP metabolism observed, as it is trending towards significance in the newly generated cell line.
A recent meta-analysis looking at the use of direct oral anticoagulants (DOAC) versus Vitamin K antagonists (VKA) for patients with APS concluded that DOACs were associated with a much higher risk of arterial thrombosis, especially in triple-positive APS, and trending towards significance for that finding across other subgroups, including non-triple-positive APS [ 11 ].
In contrast, EXTEND demonstrated functional independence at 90 days when adjusted for age and stroke severity (adjusted risk ratio 1.44, p=0.04) with the unadjusted risk ratio trending towards significance prior to early termination of the study [ 16 ].
Mechanical sensitivity of the ipsilateral paw was significantly reduced in the Magi-1 knockdown mice on day 15 and trending towards significance on day 20 compared to the control mice (Fig. 1 D).
P ≤ 0.05 were considered statistically significant, while P values 0.051–0.1 were considered to be “trending towards significance”.
Additionally, both groups showed decreased IMAT with the difference between groups trending towards significance.
An increase in macromolecules at 0.9 ppm trending towards significance has been reported previously in response to a pro-inflammatory 1 mg/kg LPS dose in developing rats 18 .
However, intramuscular fat was significant between groups and subcutaneous adipose tissue was trending towards significance ( Table 1 ). 2.2.
Additional effects trending towards significance ( p FWE < 0.10) were observed in sections of the inferior cerebellar peduncles and the SLF I (see supplementary Figure S1 ).
However, in line with Choung et., women were trending towards significance in the PWAG groups both in 2000 and 2011 [ 8 ].
However, several other interactions that were significant in hippocampus were trending towards significance in cortex; for example, Homer_NMDAR1 and _NMDAR2B were increased by 1.29 and 1.37-fold in the cortex, respectively, but were not significant by ANC criteria (see Additional file 1 : Table S1).
This sexual dimorphism was statistically significant or trending towards significance in all three replicate populations (Figure 1 ).
Both multivariable analysis for LA size (Table 5 ) demonstrated that EFW was the only independent determinant of LAA (beta 0.0007 p < 0.01) with Maternal DM trending towards significance (beta 0.1, p 0.09).
The maximal relative volume increase is obtained in the lateral ventricles, with total relative ventricular volume trending towards significance, as well.
With age as a covariate, the relationship between total sleep time and TMT-B (secs) was trending towards significance.
At p ≤ 0.05 and 0.05 < p ≤ 0.10, treatment effects were deemed significant or trending towards significance, respectively.
While our finding for readmission risk associated with increasing age was trending towards significance at the 7% level, it is supported by prior work highlighting older adults as a uniquely vulnerable group that may benefit from comprehensive transitional care [ 3 , 7 ].
sham) on ACC in the late learning phase was trending towards significance, F (1, 47) = 5.86, p adj = 0.058, η 2 = 0.023, after applying a Bonferroni multiple comparisons correction.
For LPP Occipital amplitude, results appear to be trending towards significance, suggesting that happy expressions when compared to neutral may not elicit a heightened amplitude with increasing language skills, with both negative and neutral expressions appearing to display a positive association with LPP amplitude.