At the same time, sample size issues could mask true associations trending towards significance (hence we used a less stringent cutoff p < 0.1).
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Finally, Model 4 confirmed the significance of VO2max (p=0.001, β=−0.192) and noted physical activity practices trending towards significance (p=0.102, β=−0.108), while nutrition practices and economic status remained non-significant predictors (p=0.378, β=0.057; p=0.785, β=0.016, respectively) (see online supplemental etable 2 ).
Figure 5A shows the representative gating strategy used to stratify CD8+ T cells, and total CD8+ T cells were significantly enriched in the combination group compared to IFN + 5Aza ( Figure 5C , p = 0.0003) and trending towards significance in vaccine alone (p=0.1207).
Error bars represent SEM, no significant differences found using two-tailed t-test; however, 26–28 ss Fgf3 Δ/Δ ; Bak Δ/Δ ; Bax Δ/Δ mutants had a higher rate of proliferation trending towards significance (p = 0.13).
The lack of significance in the comparison between the models considering HLA-DRB1 + all associations and HLA-DRB1 + old associations should be interpreted with caution given the relatively small sample size of this study and the p value trending towards significance ( p = 0.13).
Interaction effect was found to be statistically significant for E/A ratio and DTE (p < 0.001 and p = 0.007 respectively), and trending towards significance for E/Eʹ ratio (p = 0.136).
Interestingly, while there were no significant differences between lesions and NAWM in pwRRMS, all contrasts, except for AREX (p = 0.87), were trending towards significance (p < 0.15).
Total sartorius volumes of the controls were smaller than those for either GRippet or GRMD dogs, with the GRippet value trending towards significance ( p = 0.159 for absolute and 0.112 for corrected).
Another review including 45 patients with eCCA ( n = 33 [adjuvant RT]; n = 12 [neoadjuvant CT]) found that 11 (91%) patients treated neoadjuvantly had R0 resections and numerically improved 5-year OS, trending towards significance (53% vs 23%; p = 0.16) compared to those who received adjuvant treatment [ 69 ].
Results for elevated depressive symptoms across all methodologies were null, however PSM results for the low cSES subgroup were trending towards significance (β = -0.16, 95%CI: (-0.38, 0.07), p = 0.171) ( Table 9 ).
We perform the same analysis with dichotomous and continuous scores as detailed above to validate our CETP genetic score, finding that our SGLT2 score is associated with decreased glycated hemoglobin (dichotomized: p=0.0000426; continuous: p=0.000044), but increased systolic blood pressure (dichotomized: p=0.0116; continuous: p=0.00149) with increased BMI trending towards significance (dichotomized: p=0.172; continuous: p=0.0708) ( Figures 1C, D ; Supplementary Table 5 ).
The interaction between imitative compatibility and group which was previously trending towards significance, was not significant when controlling for depression and anxiety subscales ( p = .18).
Relaxing tracks did not significantly reduce pain intensity compared to their controls, however the effect on pain unpleasantness was trending towards significance when compared to scrambled music [MD = −2.51, t (55.4) = −1.34, p = 0.19] and silence [MD = −3.17, t (55.6) = −1.84, p = 0.071].
Multiple logistic regressions (backward variable selection) were performed using variables trending towards significance ( p <0.2) at univariate analyses, to determine factors independently associated with remission at month 12 and 24 with anti-IL-5/Rα biologics.
A single unadjusted model was used, including findings on univariate analysis trending towards significance (p < 0.2) or clinically relevant predictors.
An SII >300 showed promise in our small transplanted cohort ( n =53), trending towards significance (median survival 90.8 months ( n =31), vs 72.2 months ( n =22), for SII <300 or >300, respectively, P =0.280).
Between the two sexual orientation groups (Table 1 ), SM adolescents were more likely to be in high school ( x 2 = 3.87, p =.049) with age trending towards significance ( t = -1.91, p =.57).
While level of education ( p = 0.058) was trending towards significance, ethnicity ( p = 0.783), physical activity level ( p = 0.684), income status ( p = 0.440), level of sleeping hours ( p = 0.348), smoking ( p = 0.936), consumption of alcohol ( p = 0.522), fish ( p = 0.647), meat ( p = 0.298), dairy ( p = 0.113), fruits ( p = 0.594), sweets ( p = 0.989) or fried snacks ( p = 0.609) were not significantly associated with hypertension (Table 4 ).
then separated patients by the method, and they found that the elevated PCPI group by the bromodeoxyuridine method had a shorter median TTP (3 years versus 6.8 years) and that the difference was not significant, but trending towards significance, for FC (4.7 years versus not reached for low PCPI group, p = 0.8), which could have been due to the low number of patients ( n = 49) in this subgroup [ 23 ].
Results: miR-29c-3p was differentially expressed between LRRK2 mutation carriers and sporadic cases, with miR-425-5p trending towards significance.
In contrast, fmn primarily contained unique isotopologues and/or pools that were rhythmic, but it is important to note that a few are trending towards significance in WT (glutathione M + 1 and M + 3 and glutamine M + 0 and M + 2).
Several microbiome genera were also trending towards significance, including increases in Psuedomonas and Streptococcus and a decrease in Bacterioides , but were not significant at the given sample size.
Temporal cortex is significantly more affected in PDD and frontal cortex, caudate nucleus, and putamen trending towards significance [ 39 ].
A value of P < 0.05 was considered statistically significant, and a value of 0.1 < P <0.05 was considered as trending towards significance.
The addition of FANA- PGK1 or FANA- ALDOA reduced the frequency of RORC + cells within CD4 lymphocytes obtained from patients with Crohn’s disease, this decrease trending towards significance (Supplementary Fig. 9a ).