Repeated measures ANOVA showed a significant main effect of time and treatment, but only a slight tendency towards significance for time*treatment interaction (main effect of time: F(7.860,337.984) = 56.832, p = 1.88 × e −57 , ηp 2 = 0.569; main effect of treatment: F(4,43) = 5.973, p = 0.0006, ηp 2 = 0.357; time*treatment: F(31.440,337.984) = 1.396, p = 0.082, ηp 2 = 0.115).
We found increases that were statistically significant or show a tendency towards significance when both sexes were considered together ( Fig. 2 B1-2; distance travelled: p = 0.003, t = 0.134; immobile episodes: p = 0.059, t = 1.951), but not when males were analyzed separately ( Fig. 2 C1-2; p > 1.000 in all parameters).
A tendency towards significance was found for differences in age at visit ( p = 0.005).
Multivariate hazard ratios revealed a tendency towards significance for the effect of the degree of surgical resection on the progression-free survival (for the degree of surgical resection: HR: 2.1; 95%-CI 1.09–4.09; p = 0.03).
While the expression of claudin-1 was also notably higher with TNFα and ML-7 compared to cells treated only with TNFα, just a tendency towards significance could be shown (one-way ANOVA: F (2,9) = 5.30, p = 0.03, n = 4; TNFα: 69.34 ± 5.08%; TNFα + ML-7: 94.31 ± 11.17%, p = 0.079).
Notably, our bCP group only showed a significant correlation between hip angle and maximal passive knee extension at T2, with a tendency towards significance at T1 ( p = 0.045).
Statistical significance was set at P ≤ 0.05 and tendency towards significance was set at P > 0.05 to P ≤ 0.10 a priori.
As indicated in Table 4 , the second hierarchical regression analysis showed that after controlling for variance explained by obsessive-compulsive and depressive symptom load at intake, entering all three belief domains in the next regression step revealed a clear tendency towards significance for the prediction of obsessive-compulsive symptoms at discharge (∆ F (3,65) = 2.68, p = .05).
With a tendency towards significance, music teachers showed higher odds of being anxious compared to non-music teachers (OR 1.34, p = 0.050).
A tendency towards significance ( p =0.05) between the distribution of predominantly hyperdense and hypodense lesions was established.
For studies on bipolar depression, there was a tendency towards significance at the same time point (SMD = −0.54 [95% CI −1.08 to 0.00], p = 0.05, I 2 = 0%).
The interaction Test Time × CARS shows a strong tendency towards significance ( β = − 0.037, SE = 0.019, z = − 1.956, p = .050) and the interaction Test Time × Ravens reaches significance ( β = 0.101, SE = 0.022, z = 4.470, p < .001).
The level of statistical significance was set at p < 0.05, p < 0.01 and p < 0.001; with p < 0.1 indicating a tendency towards significance; and p ≥ 0.05—lack of statistical significance.
SMR analysis also found that there was a tendency towards significance in the connection between high expression of the NPC1L1 gene in adipose subcutaneous and lower IPF risk (OR = 0.85, 95% CI: 0.73 – 1.00, P = 0.051) (Table S20).
Notably, there was a tendency towards significance regarding the length of hospital stay, which was higher in non-survived patients ( p = 0.051).
In particular, there was a tendency towards significance for the exercise duration (F 1,6 = 5.89, p = 0.051, η 2 p = 0.50), and a significant interaction between exercise duration and hemicycles (F 1.54,9.24 = 6.15, p = 0.025, η 2 p = 0.51).
For the multivariate analysis of PFS, the same statistically significant variables were evaluated, RECIST being the only one with a tendency towards significance ( P = 0.051, HR = −0.54).
The increased abdominal pain and bloating after treatment showed a tendency towards significance, p = 0.052 and p = 0.079, respectively, whereas diarrhea was not significantly influenced by the treatment (Table 1 ).
In group 2 tendency towards significance was demonstrated for changes in the BMD of the femoral neck from the second to the fourth year of treatment ( P =0.052).
In case of Shannon entropy, a tendency towards significance was found (e.g., for 5 s window p = 0.052; see Figure 2 C).
In the primary comparison between Groups C and A, Group C demonstrated significantly better reduction in GEA scores at Day 28 (p = 0.007) ( Table 2 ) and a strong tendency towards significance at Day 56 (p = 0.052).
No other channels increased 20 Hz power during the EC condition, although Oz showed a tendency towards significance ( F (2,15) = 4.99, P = .0524) ( Fig. 5d ).
The difference in mean number of PDP sessions between good and poor groups showed a tendency towards significance ( p = 0.053).
Using the ELISA based on a specific antibody to trout fibrinogen, the concentration of Atlantic salmon fibrinogen gave, in comparison with healthy serum, a significant increase in samples from salmon with PD ( p = 0.023) and a tendency towards significance in serum from fish with CMS ( p = 0.053) was found (Table 6 ).
Significant reductions were found in the studies, which had assessed the effects of grape extract (WMD: −0.72 mg/L, 95 % CI: −1.31, -0.13; P=0.016), and a tendency towards significance was observed in the studies, which had prescribed higher amounts of grape polyphenols (>200 mg/d) (WMD: −0.67 mg/L, 95 % CI: −1.34, 0.01; P=0.053).