“quite significant”

Despite these limitations, the power of the study is quite significant (n=1 05 600).

Moreover, in other fields, the influence of natural product structures is quite significant, and the development of anti-infective drugs also relies on natural products and their structures, which shows that the exploitation of natural products and/or synthetic derivatives of their new structures to discover and develop the final drug entities, is still practical as well as popular [ 13 , 15 ].

However, the differences in crack tip opening loads explain a quite significant influence of the deposition direction on the fatigue life.

The NBO analysis showed that the Tb-centre carries a quite significant positive charge (1.694e), and significant α-spin density (6.065e), accounting for most of the unpaired spin in the 7 A neutral model.

While there is almost no activation at the lower temperatures (−30 °C and 0 °C), the energy absorption of the lateral honeycombs at the higher temperature levels, especially at +30 °C and +60 °C, is quite significant.

We also found quite significant differences in the amino acid composition of synbio “milk”, compared to bovine milk, including substantially lower levels of essential amino acids, most notably histidine, phenylalanine and valine.

However, the earnings quality models have quite significant drawbacks that make it difficult to use them to correct bankruptcy prediction models for the purposes of this article.

This is quite significant: since both LTNPs and HIV exposed but seronegative (HESN) individuals are able to control the infection naturally, they may express a similar cytokine profile; given the potential of these two chemokines, the down-regulation of these chemokines during the aviremic phase may offer some protective effect.

obtained quite significant positive results in the detection of cefotaxime and ceftazidime hydrolysis for the same incubation time, compared to the use of qualitative spectrum interpretation in ESBL-producing Enterobacteriaceae [ 35 ].

In turn, for ADN3, the difference between relative free Gibbs energies was quite significant (1.50 kcal/mol), which is a consequence of spherical hindrance generated by the phenyl ring in the second ADN3 rotamer.

Furthermore, the differences were quite significant, as the values of these indicators in rodent habitats were typically more than 1 time higher than the Chinese baseline soil values.

A quite significant shift of these peaks to higher wavenumbers is observed for humins after mixing with bitumen, suggesting a modification of the chemical environment of humins.

Therefore, the observed difference is quite significant. 3.3.

Comparison of QM results (BJ) for isolated and WC-paired bases The differences of QM-calculated geometry between isolated and paired bases are quite significant, with RMSD( d ) of 0.010–0.018 Å and RMSD( a ) of 0.94–1.29° (Tables 2 ▸ , 3 ▸ , 4 ▸ , 5 ▸ , 6 ▸ and 7 ▸ ), except for adenine, where they have no significance, regardless of the reference base pair, AU or AT (Table 1 ▸ ).

The improvements in precision and F1 - Score are quite significant, which indicates that the balanced dataset enables the model to identify targets of this category more accurately, while maintaining a good level in the ability to recall targets.

43 , 44 investigated that glass-coated plastic tubes used for obtaining PRF actually shed their silica-coatings into PRF membranes, thus embedding silica particles at quite significant levels within PRF clots.

The costs associated with institutional investigations are quite significant.

The predicted number victims from nervous system disease are quite significant: in 35 years the increase is almost 5000 more deaths per year, and in only 10 years the predicted increase is 3000 deaths.

Since brain tumors are uncommon in the F344 rat and B6C3F1 mouse plus the fact that the control rates are very con- stant, even a small chemically associated increase in brain tumors may be quite significant.

The coulombic efficiency (CE) of the system was lower as compared to the values reported in literature due to the toxic nature of the azo-dye [ 20 , 25 ].The highest coulombic efficiency of 10.36%was obtained for 200 ppm of ANB( Fig 3B ), which is slightly lower than the value reported by Bakhshian et al.[ 20 ] but much higher than the values reported by Zhang et al.[ 39 ].The toxic effects are quite significant at higher concentrations of ANB (e.g. 400 ppm) resulting in to lower CE value.

On the one hand, the increase in the molar fraction of Eu from 0 to 0.08 in the mixed Ln-MOF preparation caused a quite significant and gradual shift of the emission color, from green ( m CB-Tb ) to orange ( Figure 4 b), as shown also by the corresponding CIE color coordinates and representative luminescence microscopy images (inset Figure 4 d).

However, the cost-effectiveness of this manoeuvre may be high for resource-challenged and/or low-resource settings.[ 3 ] Surgical management of IHPS has traditionally involved a Ramstedt's pyloromyotomy using a classical RUQ incision.[ 4 ] Although, effective at providing excellent exposure of the pylorus, this method results in an abdominal scar that grows with the patient, often becoming quite significant with time.

The latter is often relatively minor in native enzymes due to favorable alignment of the donor and acceptor groups within the active substates 19 , 25 but can become quite significant when the protein is perturbed by, for example, site-specific mutagenesis. 43 , 44 The recent observation of an unusually high room-temperature KIE of ca. 500–700 for an active-site double-mutant L546A/L754A of SLO (DM-SLO) 45 was shown to be fit within a vibronically nonadiabatic PCET theory and to arise from a significant increase in barrier width (i.e., a longer equilibrium DAD), resulting in poor overlap of the reactant and product proton vibrational wave functions.

The spread of body weight in the examined patients is quite significant: from 39 kg to 125 kg, with the coefficient of variation equal to 24%, which, considering the number of all patients (115), makes it impossible to separate appropriately numerous subgroups with similar body weight.

In this study, the length of hospital stay was also shorter in the LISA group although the results were not statistically significant but the reduction of seven days of hospital stay is clinically quite significant and has a major social and economic impact, especially in the backdrop of LMIC.