Available data on pediatric populations show controversial results, ranging from the absence of relevant changes in anti-seizure drugs' blood concentration ( 15 ) to subtle changes in topiramate, levetiracetam, phenobarbital, and carbamazepine and possibly significant changes in valproate concentration under the influence of KDT ( 16 ).
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“possibly significant”
In the literature
A possibly significant effect was only seen in one experiment on one measure (reduction of RMS power in the treated group).
Statistical analyses All parameters of in vitro angiogenesis and clonogenic activity, as well as antigen expression measured before and after treatments were compared with the Wilcoxon matched-pairs signed ranks test to evaluate possibly significant changes.
This elaboration is also useful when obtaining new, possibly significant data from the raw signals.
Moreover, the three above conditions point to possibly significant associated events: activation (1); deactivation (− 1); null-activation (0).
In both of these cases, the implementation of routine use of the technologies in the NHS could have required substantial infrastructure or training requirements and possibly significant irreversible costs.
PharmGKB pathways are evidence-based diagrams that depict a drug’s pharmacokinetics (PK) “and/or” pharmacodynamics (PD) concerning significant (or possibly significant) Pharmacogenomics (PGx) associations.
Further, the DFT calculations do not take into account the role of entropy in the displacement experiments which could have a minor but possibly significant contribution in determining the displacement trends.
In the literature, the occurrence of errors during the transcription of data from paper into electronic forms such as spreadsheets is a well-known phenomenon with possibly significant outcomes [ 10 , 11 ].
In 17 of the 155 (11 %) patients possibly significant lesions were detected, which required further investigation by means of gastroduodenoscopy (n = 8) or balloon-assisted endoscopy (n = 9).
Apart from a calibration error, other possible artifacts such as the patient's head spatial orientation have been previously evaluated and discarded by other authors as possibly significant modifiers of gain values on normal subjects ( 10 ).
Patients with lower preoperative PROMIS scores (< 35) may be counseling regarding the possibly significant changes that are anticipated in their PF during early and late (6 weeks and 1 year) postoperative time periods.
Previous studies that examined the introduction of the CKD-EPI 2021 equation also noted possibly significant systemic overestimation and poorer prediction accuracy in patients with advanced age. 12 , 26 , 29 Studies also found significant reclassification in patients with more severe GFR categories toward lower (less severe) CKD categories in non-African American and Asian populations. 12 , 26 , 29 The Eu
Secondly, direct measures of infection, as determined by RT-PCR or lateral flow tests, are possibly significant underestimates of the true infection rate.
Those of us who work in Clinics are from time to time presented with the problem of a child referred because of odd behaviour and backwardness at school, whose testing and pre- liminary psychiatric observation lead to the conclusion that the child is ineducable, yet one cannot rid oneself of doubt as to the conclusiveness of the early diagnostic procedures, because, for example, of certain patchy ranges of ability or a possibly significant pattern of emotional factors in the background.
It is worth noting that because we did not measure with standards to compare with, our measurements were only oriented to identify a possibly significant Fe contamination.
Periadrenal fat volume is another possibly significant factor that we could not evaluate.
baumannii , including by mediating a possibly significant increase in carbapenem susceptibility ( Abdi et al., 2020 ).
This is remarkable because the aim of a meta-analysis is often to combine all available primary studies, commonly including a majority of non-significant primary studies, in order to obtain a more precise and indeed possibly significant effect estimate in the meta-analysis.
Then, the plots of individual random effects (empirical Bayes estimates) ( 29 ) versus covariates were used to screen possibly significant trends in the data.
It is likely that the difference would have been greater and possibly significant had more samples been available.
No statistically significant difference was found in the fit between Model 1 and Model 5 since p = 0.834 > α = 0.05, so Model 5 consisted the base to identify possibly significant interactions (MAP and Group, PAP and Group, P-STR and Group).
An additional possibly significant difference between these studies is the nature of the CWD isolate used.
We made this decision in order to be able to better investigate the area of children’s emotional responses on a spectrum that could be possibly significant at a clinical level.
As another possibly significant feature of autophagy induced by MMR, it is considered that MMR may prevent the accumulation of abnormal proteins.