“possibly significant”

This has possibly significant implications in the deployment of recently developed MCL1-targeted BH3 mimetics that are currently entering the clinic.

Conclusion These findings indicate that apoC-III lowering will have a marked effect on TRL and remnant metabolism, with possibly significant consequences for cardiovascular disease prevention.

Such a result could be explained by the small number of events registered, which lowered the statistical power to detect a possibly significant difference.

30 times higher than free Dox treated ones, signifying the possibly significant reduction of cardiotoxicity, which is a dose-limiting side effect for Dox 52 , 53 .

5 This is a subtle difference, but possibly significant when trying to anatomically repair the glenoid labrum.

The so-called “manual” SP determination described in refs ( 32 and 33 ) is quite user-dependent, however, and hence suffers from possibly significant uncertainties, in addition to low experimental repeatability.

The factors that showed possibly significant associations (at the p -value of 0.1) with suicide attempts in independent sample t -tests and Chi-square tests were included in the multivariate analyses as independent variables.

Using this assay, the parent tumor and all clones were susceptible to lysis to the same degree, again suggesting the presence of a similar target determinant on all clones, which is recognized by CTL with functional specificity for C1 8 only (Table I). Epitope density was also considered to be a possibly significant parameter for discrimination between regressor and progressor clones.

The panel members concluded that for most PICOs, there is possibly significant uncertainty about or variability in how much people value the critical outcomes.

This study design allowed for the exclusion of the possibly significant impact of excessive adipose tissue on chaperone expression, since a relationship between Hsp70 levels and obesity had previously been reported by Xing et al. in a pregnant mouse model [ 49 ].

The biopsy of our patient revealed the thickness of the cartilaginous cap to be of 3cm, which indicated a possibly significant malignant potential.

To find out the DEGs which have been identified, we compared the possibly significant genes from the GSE125564 and GSE29801 datasets with genes in the CDC-Public Health Genomics and Precision Health Knowledge Base (PHGKB; version. 6.3) ( https://phgkb.cdc.gov/PHGKB/phgHome.action?action = home ).

Locations of possibly significant NifA, σ N recognition sites upstream of genes and potential transcription terminators downstream of genes were also presented in Table.3 .

By examining these associations in vitiligo patients, this study discusses a possibly significant but neglected aspect of holistic dermatologic treatment.

A smaller—but possibly significant—decrease in the ratio of downstream:uncleaved RNA was noted for three additional mutant strains ( Figure 4D ).

Ropivacaine, the only chiral agent of the LAs tested, is structurally similar to bupivacaine but has lower lipophilicity (i.e., similar to lidocaine) and these distinct properties should be considered as possibly significant for the observed differences in drug activity.

While open-mindedness was a considerable predictor of inclination to all three outcome measures, CRT was predictive of lower adherence to stricter hygiene maintenance and lower support of restrictive COVID-19 policies, albeit these effects were weak and possibly significant due to the sample size.

33 , 34 Factors that have been reported once as possibly significant but have not been confirmed in other reports include presence of antibodies against coronavirus, spumavirus, or Borrelia burgdorferi . 26 , 39 Less is known of the natural epidemiology of the non– B. henselae Bartonella species that infect cats.

Furthermore, the analysis of this dataset illustrates how a very reduced number of fits per protein (one to 34) allows to capture any possibly significant phospho-peptides of a protein.

After secondary analysis including replication there was no evidence of association with either previously published first year response genes [ 7 ] or with polygenic predicted height score; however, several loci were identified as possibly significant.

This study provided two additional pieces of possibly significant STRICKLAND ET AL. information.

It is possibly significant to protect the vulnerable on days with low air pressure, especially those younger than 65 years.

Such sample heterogeneity often leads to “flattened” and, possibly, also distorted CD curves due to heterogenous light absorption and possibly significant light scattering ( 32 , 33 , 38 ).

It is also possibly significant in regard to cleidocranial dysostosis that ossification of the clavicle and mandible are almost synchronous, the ossification of the clavicle preceding that of the mandible it may be only by a few hours.

Furthermore, when considering that the objective of most orthopedic surgeries is to restore function and ability, not assessing the fiscal implications of such objectives ignores a possibly significant benefit provided by orthopedic interventions.