Taking the partial significance descriptors discussed above as an example, we suggest adjusting the large ring counts to decrease the molecule’s hydrophobic surface area and optimize ring connectivity in order to control the number of five-membered aromatic rings to decrease the potential for reactive metabolite formation and reduce the likelihood of generating toxic intermediates.
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The non-significant difference in the internal dataset and partial significance in the external dataset indicated 3DAD’s capability in generating trustable thin slices for downstream analysis. 3.5.
However, the argument herein gains only partial significance owing to the limitations which should be addressed in future studies.
While the decrease in IOP in the entire MIGS cohort was significant, individual analysis of stents yielded partial significance, which is most likely attributable to the small sample sizes of the individual groups.
However, some case studies have found statistical significance for some of the MI domains (e.g., Dolati and Tahriri, 2017 ; Yidana et al., 2022 ), or partial significance for one but not the other domains (e.g., Rogowsky et al., 2015 ).
Other sociodemographic variables, including age, income, and health anxiety also showed partial significance, while education, gender, and psychosocial factors (e.g., trust in doctors) exhibited no consistent associations.
Our results showed partial significance about mediating role of economic growth between solidarity and tolerance and the results are in accordance to ( 52 ).
The study of the association between the total CSHQ score and its subscales with NSS, ENSS and PNIF values documented the partial significance of these comparisons ( Table 2 ).
Nonetheless, data analysis on the increased uptake of General Practice only shows a positive trend with only partial significance, although the low response rate may have had led to distortions.
The c-Fos expression of morphine during extinction showed partial significance on three specific neural substrates (i.e., PrL, IL, and LH) compared to the saline group.
This partial significance may be due to the relatively small sample size or to the exclusion of participants with psychiatric diagnoses, which may have reduced variability in distress-related measures. 6.6.
Under the microaerobic condition, the deletion of bktB markedly decreased the 3HHx incorporation (0.6 mol%), implying partial significance of bktB in the pathway as well as function of other thiolase paralog(s) for the condensation.
We also find the partial significance of CSR × CG_Index in the case of Islamic funds only in model 2.
These results contrast with a Chinese study that found a partial significance between knowledge and attitudes toward genetic testing (Zhang et al., 2020 ).
Moreover, we found only a partial significance in the smaller model (OLMo-1B), and a marginal advantage for the larger model (OLMo-7B).
Regarding the importance of triadic interactions for the molecular function of the ULK complex, we observed their partial significance for ULK1 kinase activity against ATG14, a component of PI3KC3-C1, in our assays ( Figure 4—figure supplement 1D, E ).