21 In another study conducted on two Swedish cohorts, Yang and colleagues reported an inverse dose‐dependent association of borderline significance for vitamin C with PD risk in women only, statistical significance for vitamin E in women, and statistical significance for β‐carotene in both men and women. 18 This discrepancy with our results may have a few explanations.
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“of borderline significance”
In the literature
Similarly for bean fiber, the inverse trend was of borderline significance (p‐trend = 0.05).
found market share to be 42% in ADDO and 25% in non-ADDO regions based on outlet survey data though the difference was of borderline significance [ 42 ].
P-values ≤0.05 and between 0.06 and 0.10 were considered statistically significant and of borderline significance, respectively.
OS also showed a 0.7-month increase in the S-1-based combination therapy group, although this was only of borderline significance.
When comparing the two groups, no statistically significant differences were found ( p > 0.05) for any of the parameters, and the mandibular divergence parameter was found to be of borderline significance.
To satisfy the proportional hazard assumption, we relaxed the criterion in the last step by allowing non-demographic variables of borderline significance (i.e. p value between 0.05 and 0.10) to be individually added into the Cox-PH regression model.
In consequence, the association between increased confidence and previous Indigenous experience was no longer statistically significant (aRR 0.86, 95% CI 0.73–1.01), and the association between the outcome and rural Australian origin was of borderline significance (aRR 0.83, 95% CI 0.68–1.00).
Sub-group analyses, even when pre-specified, can lead to over-interpretation of findings of borderline significance.
All results with a two-sided p level ≤ 0.05 were considered statistically significant, whereas a p value between 0.05 and 0.10 was considered of borderline significance.
Formally, the estimated risk differences for the <50 copies/ml cut-off indicated in both the intention to treat and per protocol analysis a higher risk difference for failure in patients with PI/r monotherapy that was of borderline significance whereas the corresponding relative summary estimates were not all statistically significant.
For right‐sided CRC, the association was of borderline significance with respect to SGLT‐2i/metformin (HR, 0.63; 95% CI, 0.40‐1.01) while SGLT‐2i had no beneficial effect (HR, 0.34; 95% CI, 0.10‐1.13).
Finally, many of the correlations were low and of borderline significance.
A high level of glucose exhibited a positive association of borderline significance with the adjusted HR for cancer diagnosis. 5.
[37] examined violence and incident suicide attempts: all three studies showed positive relationships, of which two were statistically significant and one was of borderline significance ( Table 3 ).
MAD and arrhythmias Interestingly, the difference in initial ECG findings at CPR between patients with and without MAD was of borderline significance, with all 24 MAD patients showing VF at first medical contact.
There were no occupations or industries for which RCC risk increased significantly as duration of employment increased, although a trend of borderline significance was observed for the agricultural crop production industry (Standard Industry Classification (SIC) 01: P for trend = 0.051), with a three-fold elevated risk among individuals employed for five or more years (odds ratio (OR) = 3.3 [95% confidence interval (CI) = 1.0-11.5]).
Besides aggressive fluid replacement, AKI was identified as a positive predictor of prolonged hospitalization while male sex was of borderline significance (Table S4, Supplemental Digital Content 1, http://links.lww.com/MPA/B397 ).
By immunohistochemistry, we also observed a reduction in the number of macrophages infiltrating both OCI-Ly1 and SUDHL6 tumors, but this was statistically significant only for SUDHL6 tumors, and only of borderline significance for OCI-Ly1 ( Figure 5 B).
The effect was of borderline significance (OR: 0.96, 95% CI: 0.93–1.00) (Comparison B13, chapter 3.1.2.).
Additionally the study confirmed 24 previously established RA loci and further findings of borderline significance were reported that will require further validation.
In addition, our findings suggest that for both sexes combined, the simultaneous presence of elevated levels of both allergen-specific IgE and total IgE may be associated with a lower risk of glioblastoma and glioma than are negative levels for both types of IgE; however, it should be noted that these associations are only of borderline significance.
A relationship of borderline significance was seen in hormone receptor positive/HER2 negative subtype (HR: 0.839; 95% CI: 0.699–1.007).
There was limited evidence that ALK mutation, the most frequently mutated gene in neuroblastoma [ 31 ], may be associated with Cluster-1, although this was of borderline significance.
The association of home-based social network [OR 1.34 (95% CI: 0.98-1.85)] and moderate positive social interaction [OR 1.31 (95% CI: 0.99-1.72)] with OHIP score ≥4 was of borderline significance.