“of borderline significance”

Moreover, multivariate logistic regression analysis for our data showed that only serial CTCs level changes were independent prognostic factors for OS, while post-treatment CTC levels, serial CTCs level changes during the course of treatment, presence of DM, LN and distant metastasis were independent prognostic factors for PFS, however the presence of DM was of borderline significance.

The hazard ratios per IQR were modest and of borderline significance however, reflecting the low exposure contrasts in these low-exposure settings.

177 Two case‐control studies also associated higher recreational PA versus none with a 30% to 60% lower breast cancer risk (most of borderline significance), with a significant decrease in premenopausal, receptor‐negative cancers (HR, 0.46; 95% CI, 0.24‐0.92). 26 Breast Cancer Mortality Is Inversely Associated With PA Before and After Breast Cancer Diagnosis Many large, observational, prospective cohort studies have associated PA before and after a diagnosis of invasive breast cancer with better outcome.

Covariates of viral hepatitis Among HIV-negative MSM, factors associated with ever having HBV infection in multivariable analysis are shown in Table 3 ; age was of borderline significance in relation to HBV infection, while the number of lifetime partners and HBV vaccination remained significantly associated with HBV status.

In contrast, although of borderline significance, mean Cu levels in wet-weight tissue were probably decreased in the VaD group.

For DEL1, we also observed increased levels of borderline significance for GRP78 and ATF3 (1.5-fold and 1.3-fold, respectively).

In addition, the p-value after adjustment was of borderline significance in our analysis.

In our analysis, we observed associations between both sPPF and ADL impairment and SB time and long sitting patterns that were of borderline significance and modest effect size.

Of interest, and of borderline significance after adjustment for multiple comparisons, children administered rapid intravenous rehydration were more commonly admitted to hospital at the index visit and received longer periods of intravenous rehydration.

These associations were modified slightly if rectal gonorrhoea was added to the model, with tenesmus becoming of borderline significance (aOR 2.82, 95% CI 0.99, 8.86), constipation becoming more strongly associated (aOR 3.45, 95% CI 1.19 to 10.04) and gonorrhoea itself being an independent predictor of LGV (aOR 4.02, 95% CI 1.17 to 13.80).

The overall fully adjusted effect of radial dyssynchrony on change in LVESV was ∼10 mL, which was less than the effect of LBBB (∼18 mL) but greater than the effect of QRS ≥150 ms (∼8 mL), which was of borderline significance.

There was only a small enrichment of borderline significance in the ORF of TGFBR2 , but after removal of sequences with a seed match to the TGFBR2 3' UTR, the signal became significant (see Additional File 1 Figure S4).

In contrast persons under 40 years showed little to no relative increase in invasive melanoma in the last two decades: young men showed a 1.4% annual increase of borderline significance and women under 40 years showed virtually no change in melanoma incidence (Table 1 ).

There were small inverse associations with carbohydrates across all exams, although the association was not significant at Y30 and was of borderline significance at Y10.

After the 2nd dose, there was again a trend to lower rates in men of fatigue (RR 0.78, p = 0.07), headache (RR 0.71, p = 0.052) and myalgia (0.68, p = 0.054), although these differences were of borderline significance.

genitalium and symptoms, whereas 1 reported a weak association of borderline significance ( 7 , 8 , 17 ).

Another limitation of this study is that the observed associations between the frequency of consumption of protein-rich foods and functional outcomes were weak and of borderline significance.

However, low levels of happiness the previous day remained of borderline significance after adjusting for neighbourhood perceptions of crime, neighbourhood perceptions of quality, and for both crime and quality.

Among women with the most Native American ancestry, MMP1 and MMP3 were of borderline significance (p artp = 0.07 and 0.06 respectively) whereas MMP9 was statistically significant among this group of women (p artp = 0.024).

18 This review also examined 13 studies of breast cancer, with 9 showing a favorable association of vitamin D markers or sunlight with decreased cancer risk, 1 showing benefit of borderline significance, and 3 without association. 18 They evaluated 7 studies of ovarian cancer, 5 of which showed higher mortality with lower vitamin D intake or lower sun exposure. 18 In addition to a possible anticarcinogenic effect of vitamin D, autoimmune diseases such as type 1 diabetes mellitus, multiple sclerosi

In the multivariate analysis, a poor Royal Marsden Hospital (RMH) prognostic score was associated with SFs (OR = 2.3; 95%CI [1.0–5.7], p = 0.06), although this was of borderline significance likely because of small numbers.

Stratification by smoking status revealed a higher risk of CDW among current smokers with at least six amalgam fillings (HR 1.89, 95% CI 1.09–3.27), while the association was weaker and of borderline significance among nonsmokers (HR 1.28, 95% CI 1.00–1.66) ( Supplementary Table 6 ).

The components of elevated BP (β = −0.095, P = 0.070) and low HDL-C (β = −0.089, P = 0.077) were also of borderline significance with that of RNase-L in regression analysis (Table 4 , Model 3 and 4, respectively).

Evidence of interaction was also observed for the GTCA haplotype, though of borderline significance (p inter = 0.061).

Due to the number of events, the most robust result concerns the risk of metastatic relapses: ERI TCP was the strongest predictor of metastasis-free survival while the pathological response resulted of borderline significance.