The association with RSV, while of borderline significance, was in the other direction.
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“of borderline significance”
In the literature
The exposure-response function for 19 sites did not deviate significantly from linearity, while a deviation of borderline significance was found for pancreas cancer.
In fact, the observed associations are characterized by high uncertainty, with wide confidence intervals; in addition, they are often of borderline significance.
Slc1a5, also known as Asct2, was of borderline significance by interactome analysis ( Figures 4A and 4B ) but has been shown to be palmitoylated 12 and is the only glutamine transporter known to localize to mitochondria. 37 Because APT1 and APT2 are each palmitoylated near their N terminus, 36 we anticipated interactions with acyltransferases.
Area of residence with high GP density showed an independent association of borderline significance (OR, 1.17; 95% CI, 0.98–1.42).
However, some studies revealed that despite a significant increase in the use of advanced treatments, the improvement in mortality rates is of borderline significance [ 14 , 24 ].
The increase for sickle cell disease HCT is clearly (>95% CI for the prediction model) significant, for thalassemia of borderline significance.
In a multivariate analysis, T factor and difference of IA chemotherapy were of borderline significance ( Table 3 ).
For three genes in the data set, KRT5, KRT6A, KRT6B , there was a significant association between gene expression and inferior prognosis unique to young women (with overexpression of EGFR of borderline significance).
Thus, a stratified analysis of the associations of the rs2292239 variant of the ERBB3 gene with T1DM did not reveal significant gender differences, since a significant association was confirmed in the group of women, while in men it was of borderline significance, which is probably due to the smaller size of the male subgroup.
High-sensitivity C-reactive protein (hsCRP) and white blood cells count were significantly higher in the OA group and the difference in platelet count was of borderline significance.
The inverse association between baseline nut consumption and total mortality was of borderline significance in participants in the upper category of baseline nut consumption in a MedDiet supplemented with EVOO group, while there was no significant association in those allocated to a low-fat control diet, who were advised to reduce intake of all fatty foods, including nuts.
Furthermore, the improvement of glycemic control in the second study was of borderline significance, warranting caution when interpreting the conclusion based on these two studies.
However, its effect on death was very small and of borderline significance, i.e., lower risk for death before kidney failure but higher risk after kidney failure when compared to no RAS blockade.
Expectedly concentrations of some pituitary hormones or hormones released by their target peripheral glands were lower in patients with hypopituitarism (and also in patients with other pituitary diseases or in all patients with pituitary diseases) than in control individuals and these differences relate to ACTH, LH, FSH (of borderline significance), TSH and, regarding peripheral hormones, to cortisol and FT3.
Of note, the genotype frequency of rs495828 of ABO in our study population was not in Hardy-Weinberg equilibrium, but this aberration was only of borderline significance.
An inverse association was observed between Mn intake and the risk of the MetS among women, whereas a positive association was found among men, although both associations were of borderline significance ( Table 3 ).
Statistically significant AST and ALT variations were found in patients negative both for HCV-Ab and HBsAg (−1, IQR=−5–2, P =0.03; −2, IQR=−7–2, P =0.003 respectively), whereas an ALT decrease was of borderline significance in individuals with positive HCV-Ab and/or Hbs-Ag ( Table 2 ).
In addition, the trend test was of borderline significance for SPC of squamous cell carcinoma of the skin with a family history compared to without a family history (3.25 [1.05–10.02] vs 0.74 [0.48–1.15]).
The prevalence of hypertension was higher in the non-poorest quintiles but was only of borderline significance, which is consistent with findings of other studies that cardiovascular risk factors are associated with the economic development and where the mean level of population blood pressure is not correlated, or only weakly correlated, with economic factors ( 25 ).
Although of borderline significance, physical therapy visits and visit intensity were greater for FFS patients.
The associations between low eGFR and other complications, including retinopathy ( P = 0.096) and cerebrovascular disease ( P = 0.023) were only of borderline significance ( Table 1 ).
In univariable analysis, lactate dehydrogenase (LDH) > upper normal limit (UNL), haemoglobin (Hb) < 12 g/dL and need for treatment and early years of registration (2010‐16) were associated with higher HBV+ rates; MZL histology and age were of borderline significance (Table S2 ).
Associations between help seeking and area-level deprivation at interview were of borderline significance among women only.
Predictors of relapse (as defined earlier) were similar to those of treatment escalation (L3, SES-CD, pANCA positivity, and B2 being statistically significant ( P < 0.05) and L1, family history of IBD, and ASCA negativity being of borderline significance).