Barely Significant
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“of borderline significance”

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In the literature

123 Taking these three RCTs together, restarting OAC was associated with reduced risk of ischaemic stroke on the one hand but increased risk (of borderline significance) for recurrent ICH. 124 The threat of ICH recurrence is daunting but many physicians will consider restarting anti-thrombotic therapy at least 30 days after the ICH. 125 The results of ongoing RCTs focusing on OAC vs. no anticoagulation (without considering LAAC) in ICB patients with AF (such as EN
38 39 On the other hand, the subgroup analysis is based on a comparison between trials; it is not robust across statistical analyses (the effect did not appear in the univariable analysis but only in the meta-regression, and the meta-regression is at high risk of over-fitting—six trials account for 92.5% of the weight), and was not prespecified; the apparent reduction in mortality with GLP-1 is both small and of borderline significance.