Vigorous physical activity showed a weak but deleterious association with medial tibiofemoral BMLs (PR: 1.02, 95 % CI: 1.01, 1.03) and the association with any knee BMLs was of borderline significance.
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“of borderline significance”
In the literature
Thus, the Heaviness of Smoking Index (HSI) was only of borderline significance in preliminary analysis [ 37 ] and concerns arose that the true importance of being dependent might be missed if the HSI was used to represent dependence so instead a dichotomous variable was used: clients who smoked >30 cigarettes per day or who smoked within five minutes of waking were coded as dependent and contrasted with all other clients.
In the comparisons of severe PPM group versus control group and severe PPM group versus moderate PPM group, the pooled HRs were 1.42 (95% CI: 1.00–2.03, P = 0.05) and 1.47 (95% CI: 1.01–2.16, P = 0.045), respectively; with a P -value being of borderline significance.
For both diseases male SIRs were higher than female ones although for Graves disease the sex difference was only of borderline significance.
The reduced mortality in surgical vs nonsurgical patients was significant in the whole cohort and in patients with diabetes, of borderline significance in patients without diabetes.
Area Townsend score was not significantly associated with the odds of CT (OR 0.97; 95% CI 0.93–1.01), although the association was of borderline significance for HT (OR 1.04; 95% CI 1.00–1.08).
Indeed, investigating the association between influenza infection and vaccination during pregnancy and autism spectrum disorder (ASD) risk in a cohort study of 196,929 children born at Kaiser Permanente Northern California, Zerbo and colleagues [ 16 ] found that influenza vaccination anytime during pregnancy was not associated with ASD risk (the adjusted HR was of borderline significance: 1.10; 95% CI 1.00–1.21).
20.2%, P = 0.068), a difference of borderline significance.
However, the mean IL-6 concentration was markedly higher in patients receiving placebo, and this difference was of borderline significance (Figure 4 ).
For both groups, odds ratios for contrasts between 2014 and 2019 were in the direction of continued lowering of the odds of ever smoking, though were of borderline significance for the whole sample only.
The achieved sample size of 59 schools resulted in estimates of effect size that were of borderline significance.
The only risk factor that was of borderline significance for the outcome of recurrence was the presence of many caregivers.
Symptomatic depression was slightly more common among children who lived in the poorest households, although this was of borderline significance (aOR: 2.0, 95% CI 1.0–3.5).
We cannot exclude the role of birth weight in our study since it was of borderline significance in univariate analysis and because this parameter was not available for all the children.
In addition, in the subgroup analysis of case-control studies, an association of borderline significance between diabetes and AMD (OR, 1.23; 95% CI, 0.97–1.56) was presented if the study by Nitsch et al [13] was excluded.
Nevertheless, we are extremely cautious about making conclusions from such subtle changes of borderline significance, as these likely represent Type 1 errors.
Whereas weak negative interactions were noted between high triglycerides and hypertension and between low HDL cholesterol and hypertension, these were of borderline significance.
However, when adjusting the analyses for parity, maternal age and time between childbirth and blood sampling in Cohort 5, the associations were slightly attenuated and the association between ΣPCB and child sex was of borderline significance; a doubling in ΣPCB was associated with an 8% increase of the sex ratio, while it was 7% for a doubling of p,p’ -DDE and 9% for a doubling of the methylmercury concentration ( Table 2 ).
In addition, C3 was still associated with a higher asthma symptom score (MSR = 1.18 [1.02; 1.37]), and C2 was of borderline significance with slightly lower MSR.
Thus, the observed association is of borderline significance.
found higher levels of mean 24 h urinary testosterone levels in a sample of 39 nights workers, but the differences were of borderline significance [ 35 ].
The factors “Harmfulness” and “Willingness” were of borderline significance.
In the mixed model, the interaction pattern was most clearly supported in unipedal stance, whereas the bipedal interaction term was borderline, and the elastography effect was also of borderline significance.
Associations of colon and rectal cancers with most of these covariates, such as age, education, household income, family history of CRC, tea consumption, cigarette smoking, intake of fruits and vegetables, were statistically significant or of borderline significance in this study (data not shown).
The review by Free et al [ 24 ] which achieved the highest AMSTAR score (9) found that mobile technology-based interventions improve glycemic control, but the effects were small and of borderline significance (MD -0.27% (95% CI:-0.48, -0.06), 5 trials, I 2 = 8.5%).