Higher Mizumoto and SINS values were found to be further independent risk factors for reduced OS in octogenarian patients receiving palliative radiotherapy for bone metastases, while the prognostic value of non-breast cancer histology was of borderline significance in the multivariate analysis.
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“of borderline significance”
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studied pericolonic tumor deposits and extracapsular tumor extension and concluded that the value of ENTE as an independent prognostic factor of stage III cancer is of borderline significance [ 6 ].
In this cohort, although the results for strenuous activities of running and jogging were of borderline significance for 2 or more hours per week, power was limited because only 3% of women reported running and jogging at this level.
Transfer of 2 embryos was a significant factor for occurrence of abnormal placentation and spontaneous cycle ET (i.e., ET without any stimulation) was of borderline significance ( P value being between 0.050 and 0.100) for absence of abnormal placentation.
Relaxing criteria to include common variants the strongest association was provided by the SNP rs7188880 (hg19 chr16:g.74664810.A>T, risk allele A, MAF =0.46, OR =1.41, P =2.15×10 −6 ), a synonymous SNP mapping to the gene encoding RFWD3 , which was of borderline significance. rs7188880 is in strong linkage disequilibrium with the missense variant rs7193541 ( r 2 =0.65, D’ =0.96) previously shown by GWAS to influence MM risk [ 6 ].
Although of borderline significance, we also observed a survival benefit with ever use of oestrogen-containing HRT.
The recently reported RESPECT-EPA trial [ 19 ], while of borderline significance for the primary endpoint, did achieve the secondary endpoint, with relative risk reductions due to icosapent ethyl therapy consistent with REDUCE-IT.
Being male, being younger, being from NZ and being from non-English language backgrounds (although only of borderline significance for those of European language backgrounds) all predicted a greater likelihood of a re-sit even after adjustment for the influence of initial UMAT percentile score.
Nuclear grade (RR 1.6) and negative ER status (RR 1.7) were of borderline significance, while tumour size, p53 positivity and carrier status did not achieve significance ( Table 2 ).
However, we have taken a parallel approach by including in our analysis not only the genes with genome-wide significance (GWAS “white zone”), but also GWAS results of borderline significance (GWAS “grey zone”) with p-values between <10 −5 .
South Africa had exactly opposite (of borderline significance) outcome of EPBF on mothers’ BMI.
However, with the exception of low serum potassium (of borderline significance) documented on the 4th hospital day, long QT was noted despite normal potassium levels, thereby excluding hypokalemia alone as a cause of persistent QT prolongation.
The OR for exposure to exhaust fumes at 0.9 was of borderline significance.
Due to the number of events, the most robust result concerns the risk of metastatic relapses: ERI TCP was the strongest predictor of metastasis-free survival while the pathological response resulted of borderline significance.
They found a difference of borderline significance in the distribution of the 157insMTTTVP insertion between patients and controls ( p value 0.037), with an allelic frequency of the insertion of 37% in patients and 28% in controls.
However, the prevalence of stunting amongst children with hepatosplenomegaly compared with children without organomegaly was of borderline significance.
Evidence of interaction was also observed for the GTCA haplotype, though of borderline significance (p inter = 0.061).
Nonetheless, it has to be noticed that, in the present study, cognitive deficits were detected only in a part of the administered tests, with some statistical values of borderline significance, suggesting that other cognitive functions resulted preserved.
Adding deprivation to this model (model G) did not significantly improve the fit, although the test for trend was of borderline significance.
In our study, current smoking was not associated with 15D, but ex-smoking remained of borderline significance.
The components of elevated BP (β = −0.095, P = 0.070) and low HDL-C (β = −0.089, P = 0.077) were also of borderline significance with that of RNase-L in regression analysis (Table 4 , Model 3 and 4, respectively).
Although the relationship with TI velocity was of borderline significance, it was in addition to a measure of LV filling pressure, e.g. a possible active process in addition to passive elevation of PAP due to elevated LV filling pressures.
The analyses considered p -values <0.05 to be statistically significant and those between 0.06 and 0.10 to be of borderline significance.
More adherent participants were also less likely to suffer either an incident CVD or CHD event, though the latter was of borderline significance (Table 2 ).
In the case of borderline significance, the interaction was further investigated with dichotomized BMI-GRS groups stratified by the median value.