In univariate analysis, we found an association of borderline significance among Ki-67 change subgroups and DFS ( p =0,0596), with fewer recurrence for patients with high Ki-67 reduction (shown in Figure 2(b) ), which was confirmed in multivariate analysis (95% CI 0,3589–0,93, hazard ratio = 0,5788, p =0,0256) after adjusting for covariates (age, tumor molecular subtype, clinical stage, and lymphovascular invasion) (shown in Table 3 ).
Indexed LV mass and peak exercise LV ejection fraction also had P -values of borderline significance ( P = 0.06 and 0.15, respectively).
Overall, the use of IMRT was associated with a 24% relative reduction (HR = 0.76, 95%CI = 0.57–1.01) in the risk of loco-regional relapse compared to 2D/3D-RT ( Fig 4 ), which was statistically of borderline significance (p = 0.06) as the upper bound of the 95%CI was just touching the line of unity.
Fasting and postmeal TG were higher and HDL and LDL cholesterol were lower in patients compared to those without CKD although all differences were of borderline significance ( p = 0.06).
Mechanistic Analyses 9‐decenoylcarnitine was related to left atrium diameter, relative wall thickness, and LV mass index in the age‐ and sex‐adjusted analyses, but following adjustment also for the traditional risk factors, these relationships were of borderline significance ( P =0.06–0.08, see Table 4 for details).
Additionally, Mlh1 , and Sfrp1 which had shown age-related expression decrease of borderline significance (1.4 fold, P = 0.06) in the Mlh1 +/- WD* group ( Table S5 ) and is a well-known gene in CRC and Wnt signaling were studied for methylation.
As pointed out by Sandercock et al , a pooling of the overall data utilising the random effects model does suggest a benefit for paclitaxel-platinum of borderline significance (hazard ratio for progression free survival of 0.84, 95% confidence intervals of 0.70 and 1.01, P =0.06).
Detection of FRE colonization on pre-transplant testing predicted for subsequent re-hospitalization ( p = 0.002); the detection of FRE colonization, including the post-transplant samples, was of borderline significance ( p = 0.06).
Maximum and likely gamma were not significant predictors of risk for can- cer of the CNS, whereas background radiation was of borderline significance (p = 0.06).
This difference was statistically significant with the fixed effect model (Mantel-Haenszel RR; 1.55; 95% CI, 1.06–2.28; P = 0.02, and of borderline significance with the random effect model (Mantel-Haenszel RR; 1.51; 95% CI, 0.98–2.33; P = 0.06).
The association between syphilis screening status and any previous adverse pregnancy outcome (ie, spontaneous abortion, preterm delivery or stillbirth) was of borderline significance (29.4% vs. 21.7%; P = 0.06).
On multivariate analyses, low expression of ULBP4 was of borderline significance for OS, PFS, and DMFS ( P = 0.060, 0.053, and 0.076, respectively).
Hence, the group by tract interaction remained unchanged, F(1,23) = 8.67, P<0.01, while the effect of group for the UF remained significant, F(1,22) = 5.11, P = 0.03, although it was of borderline significance (P = 0.06) when correcting for multiple comparisons using the Bonferroni procedure.
The effect was statistically significant for nurses but only of borderline significance for physicians (95% CI 1.0–3.8, p = 0.06). 4.
10 Interestingly, we found decreased risk of progression from MGUS to WM of borderline significance ( P =0.06) which is consistent with the findings of the main analysis showing an association of DM and decreased risk of WM.
Chi2 suggested that the increase was of borderline significance (P = 0.06).
There was some indication that Mandinka were more likely to have malaria than Fula children, although the result was of borderline significance (OR comparing Mandinka to Fula children = 1.52, 95% CI: 0.98–2.36, P = 0.06).
When combined with climatic risk factors, the individual effect of water deficit was of borderline significance ( p -value = 0.06, ANOVA).
This decrease was of borderline significance once women already on ART at enrollment were excluded (0.9% pre-B+ vs. 0.2% post-B+; P = 0.06).
For β-blockers, the association was weaker and of borderline significance (OR = 1.81, 95% CI 0.98–3.37; P = .06), suggestive of a trend. 4.
β = 0.82, p = 0.001) and was of borderline significance at maximal urine concentration (St. β = 0.58, p = 0.06).
After controlling for various covariates, insomnia indicated a high likelihood of poor self-rated health (Odds Ratio [OR] = 1.58, 95% confidence interval [CI] = 1.27–1.96, p < 0.001), self-rated happiness (OR = 1.58, 95% CI = 1.26–1.97, p < 0.001), and the MCS (OR = 1.42, 95% CI = 1.14–1.78, p = 0.002), and its association with poor PCS was of borderline significance (OR = 1.30, 95% CI = 0.99–1.72, p = 0.06).
However, from baseline to week 16 a decrease in VAS of 21.4% (0.43 cm) was observed for patients in the IVIg group, and from baseline to week 40 for the combined cohort of patients a decrease of 22.4% (0.52 cm) was seen; both decreases were of borderline significance ( P = 0.06 and P = 0.05, respectively).
These improvements were statistically significant except for the obstructive micturition domain, which was of borderline significance ( p = 0.06) in the sacrospinous hysteropexy group.
When we compared the frequency of these haplotypes in vCJD versus the Dutch control population, only the difference in H1j (3% in controls versus 7% in vCJD) was of borderline significance (p = 0.06).