Barely Significant
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“of borderline significance”

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In the literature

Median AAO in those with a depressive onset polarity was associated with the same two variables (HR for comorbidities: 0.44; 95% CI: 0.29, 0.68; HR for year of birth: 1.29; 95% CI: 1.04, 1.58); sex was of borderline significance in this model (HR for male sex: 1.28; 95% CI: 0.94, 1.68).
All the adjusted HRs above were accounted for smoking-alcohol interaction Significant trends suggesting increased risk with daily smoking amount (p for trend = 0.01) and cumulative consumption (pack-years) (p for trend = 0.01) were observed in the adjusted HRs of Model 1, but the trend was of borderline significance for smoking duration (p for trend = 0.06) (Table 2 , Model 1).
In multivariate analysis, the only factor that was statistically significantly associated with serological response at 6 months of follow-up was age less than 34 years (adjusted odds ratio [OR], 1.96; 95% confidence interval [CI], 1.247–3.080; P = 0.004), while the associations between secondary syphilis (adjusted OR, 1.499; 95% CI, 0.943–2.383; P = 0.087) and CD4 <350 cells/μl (adjusted OR, 0.672; 95% CI, 0.425–1.065, P = 0.091) and serological response were of borderline significance ( Table 3 ).
On the other hand, for the eight comparisons from seven trials with modern imputation techniques [ 38 , 39 ], [ 43 - 45 , 47 , 49 ], the SMD was −0.34 [95% CI −0.51 to −0.18], indicating a small clinical effect (of borderline significance) in favour of CCBT.
This may be partly due to the fact that there are significant correlations between uPA/PAI-1 and SPF - a clinical finding that corresponds well with experi- mental evidence suggesting that cell proliferation is stimulated after internalization of the uPA/PAI-1/uPA-R complex. Ploidy was not a statistically significant factor for DFS and only of borderline significance for OS.