“of borderline significance”

Another site in the same gene was significant for HOMA-IR and of borderline significance for insulin ( P = 1.29 × 10 −7 and P = 3.36 × 10 −6 , respectively).

Although no gene achieved genome-wide significance in the meta-analysis (Bonferroni-corrected p < 2.4 × 10 −6 ), the meta-analysis p-value for the germ cell-specific gene, GGN , was of borderline significance (p = 7.1 × 10 −6 ).

Lupus nephritis was more common in Subgroup 2, though it was of borderline significance because age was added as a covariable, which was a significant component of the model ( P = 1.5 × 10 −5 ).

Within group follow-up comparisons revealed that the LPC was highly significant in the CN group [ t (33) = 5.2, p < 0.0001], but of borderline significance in the a-MCI patients [ t (23) = 2.1, p = 0.05].

Subjects with malnutrition based on the GLIM criteria tended to be older (a p of borderline significance) and had lower MNA-SF scores ( p < 0.0001).

In the Scottish population, we demonstrate a highly significant association in IBD ( p < 0.0001) and UC ( p < 0.0001), and an association with CD of borderline significance ( p = 0.03).

By multivariate linear regression both age and creatinine clearance were highly significant predictors of NT-proBNP levels (P < 0.0001), while hematocrit was of borderline significance (P = 0.06).

When analysed separately, there was a highly significant association between haemoglobin and serum ferritin in patients with ID ( r = 0.16, p = 0.0004), whereas in patients without ID, this association was only of borderline significance ( r = −0.09, p = 0.03).

Although of borderline significance and hypothesis generating, after correction for the 90 TFs assayed, there was evidence for enrichment of SPI1 (alias PU.1), ( P =0.0007, P adjusted =0.063), which regulates PRDM1 and its downregulation is required for MM cell growth 19 .

The CRP level showed a highly significant correlation with tumor stage ( p = 0.001) and an association of borderline significance with smoking ( p = 0.021), whereas no statistically significant associations were observed between CRP levels and age or sex ( Figure S1 ).

The traditional change between visits 2 and 3 was of borderline significance in both groups, but the addition of the then-test again led to highly significant actual change (p < 0.001 in both groups).

Breakpoints of borderline significance ( P > 0.001) are removed in our default segmentation when mirrored allelic fractions (1- allelic fraction if allelic fraction >0.5) of known heterozygous germline variants (dbSNP) are not significantly different ( P > 0.2, two-sided t -test) in the corresponding neighboring segments.

In regards to the APOL1 region and fluid loss, the association remained below our significance threshold for rare variants (0.00109) in the random effects meta-analysis conducted in the entire population ( P = 0.0008), was of borderline significance in the fixed effects model in the entire population ( P = 0.0019), as well as both models limited to only Caucasians (fixed: P = 0.0013, random: P = 0.002).

A highly significant (p=0.002) moderate positive correlation was recorded in patients aged <50 and moderate positive correlation of borderline significance in males (r s =0.324, p=0.058).

There was an improvement in the confidence of the etiological diagnosis with the number of certain diagnoses increasing from 23% to 100%, which was statistically significant for reader 2 and of borderline significance for reader 1 ( P = 0.002 and 0.052, respectively) when unenhanced phase and SIM were added.

This was nominally significant (p = 0.002), and after correction for 4 pro-inflammatory genotypes and the 4 measures investigated this finding remains of borderline significance (16 tests, corrected p = 0.03).

Small LDL IIIa and IIIb decreased at 1 year, with LDL IIIb maintaining significance at 2 years (− 23.1% at 2 years, P = 1.0 × 10 –3 ) where it was lower compared to UC ( P = 1.0 × 10 –3 ) (Table 1 ), while the reduction in LDL IIIa at 2 years was of borderline significance after Bonferroni correction ( P = 3.0 × 10 –3 ).

LTA was of borderline significance (p = 0.051) in the multivariable model once BOT D50% was included, although it was highly significant (P = 0.0032) without BOT D50% in the model.

At follow-up, the percentage of children receiving an antimalarial monotherapy in the intervention arm was lower than that in the control arm, although this was only of borderline significance in the adjusted analysis (difference in means: −10.5%: 95%CI: −3.9%, −16.9%; unadjusted p = 0.0036; adjusted p = 0.0518).

Presence of hyposalivation based on unstimulated salivary flow rate (IUS), although highly significant in the simple logistic regression model (OR: 2.02, 95% CI: 1.24–3.27, p-value = 0.004) was only of borderline significance when adjusted for confounders (OR: 1.68, 95% CI: 1.01–2.79, p-value = 0.046).

Only PIK3C2G cg17881542 was present in this dataset and, although the data were of borderline significance (log-rank test, p = 0.004; HR = 0.77, 95% CI 0.59–1.01), we could observe that high methylation levels of cg17881542 were associated with favorable prognosis in HNSCC (Fig. 5 b).

It is noteworthy that the trend for the number of implants was of borderline significance (S-score = 8, Sens slope estimate 8.44, Mann-Kendall statistic = 1.959, P = 0.0500) and for the number of detox's was highly significant (S-score = 19, Sens slope estimate = 14.56, Mann-Kendall statistic 2.853, P = 0.0043) as illustrated for both variables in Figure 4 .

An interaction indicative of relatively lower activity during mental illness trait self-evaluation in schizophrenia was of borderline significance ( p < 0.0059) in one area: right inferior parietal lobule (BA40); peak Talairach coordinates, 47, -33, 37 (see Figure 3 ).

However; there was one statistically significant difference at 6 months (MD=−0.08), although this is not clinically relevant and can only be considered of borderline significance (95% CI –0.13 to –0.02), despite the low p value (p=0.007), see figure 2 d2 .

The greater proportion of patients with prostate cancer treated with aMRI LINAC were treated at an academic center versus patients with prostate cancer treated with IMRT was of borderline significance ( P = .007).