Logistic regression to predict for the response after galcanezumab treatment A binary logistic regression model was employed to predict the response to galcanezumab by entering significant and nearly significant promising variables selected from the preceding analyses.
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p=0.0579p=0.06
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In the present study, we observed a nearly significant DEX-induced increase in IL-6 and TNF-α levels in the HT also ( Figure 4 A and Figure 5 A).
The correlation for NSS and TMT-B was nearly significant.
Statistically significant, or nearly significant, increases in attainment were observed at week 27 across two measures, the Controlled Oral Word Association Test (COWAT, a verbal fluency test) and the Paced Auditory Serial Addition Test (PASAT3, a working memory/processing speed task) ( P = 0.074 and P = 0.0356 respectively, paired 2-tailed t test); however, after applying the Bonferroni correction for multiple comparisons, these P values no longer reached significance.
These motor functions also showed significant ( p < 0.05) or nearly significant associations with AD-PRS based on either IGAP, CCACE, or both in a participant group of Alzheimer’s dementia ( N = 557).
Patients with co-morbidities were more likely to present PCI, although only the association of having a diagnosis of a lung disease (asthma, chronic obstructive pulmonary disease, chronic bronchitis, surgery for lung cancer, pulmonary emphysema, and pneumonia) was nearly significant (age- and education-adjusted OR, 95%CI: 1.87, 0.97–3.60).
For the Mir183/96 dko homozygotes, we obtained eight networks for which their upstream regulators were given a significant or nearly significant z -score; Bdnf, Gh, H2afx (also known as H2ax), Kcna3, Kit, Myocd, Prkaca and Pth, which explain between them the misregulation of 14 genes ( Fig.
Moreover, significant inverse correlations between plasma total polyphenols and total cholesterol, triglycerides, TG/ HDL-C ratio and AIP, nearly significant negative associations with LDL-C and T-C/HDL-C, as well as inverse relationships between plasma total polyphenols and muscle damage (CK) and lipid peroxidation (TBARS) markers, seem to strongly support our presumption that the beneficial changes in lipid profile and the blood antioxidant defence status of our junior athletes were mostly due to 6 weeks’ intake of the polyphenol-rich fruit and berry juice blend.
The Family motive was nearly significant, and teaching experience, permanent employment, and gender were significant predictors for moderate PA.
However, it seems presumptive to suggest bringing nearly significant results into clinical practice; hence, additional data will be warranted to ensure the implication of ‘indeterminate CN’ is robust.
S3 ), they achieved nearly significant convergence over a period of time that cumulatively accounts for ∼4.4% of the evolutionary history of the family ( Table 3 and Fig. 3 ).
However, this is not supported by our findings in patients admitted with mild hyponatremia, where no difference in mortality was seen and where a nearly significant higher mortality was observed.
From the upper two panels of Figure 4 , it is apparent that there were nearly significant correlations between optical and retino-neural factors (F1 vs.
A p-value of less than 5% was considered statistically significant or nearly significant for p [0.05-0.08], considering the small sample size.
The mediating effect of hypertension was statistically significant in the whole population and in the female population, and nearly significant in the male population.
In regards, immunohistochemistry and RT-PCR experiments in renal disease confirmed a nearly significant decrease in AVPR2 protein and mRNA expression [ 55 ].
Compared to control plants, plants with 25% of their leaf area consumed had significant, and plants with 50% of their leaf area consumed nearly significant, reduction in their flower production during the year following experimental damage.
These abbreviated scan protocols depicted the same sensitivity and nearly significant specificity compared to the FDP.
The presence of a nearly significant difference between the total DES scores of patients with and without injury in Group II may be due to the effects of the absorption factor in this group.
The factor that was most nearly significant in relation to plaque presence was the presence of hypercalciuria.
Among the two studies that explored GI in relatives of BD, the first did not report differences between affected and unaffected offspring of BD and HC without a family history of BD in the IFG (Drobinin et al., 2019 ), a region previously proposed as a candidate endophenotype for BD (Cattarinussi et al., 2019 ), while the second showed a nearly significant reduction in GI in first-degree relatives of BD with cluster A personality disorder compared to HC (Nanda et al., 2014 ).
In the arthrogryposis multiplex congenita model, the administration of FcRn antagonist to pregnant dams infused with human acetylcholine receptor-specific antibodies resulted in nearly significant decreases in pathogenic antibodies in the dams, and a major decrease of these antibodies in the fetuses 239 .
Nausea and rash describe mainly the pneumonia symptoms because they produce the highest positive deviates in that disease; headache, fatigue, and myalgia (nearly significant deviate) point positively to the H1N1 disease; and no particular symptom is present at maximum positive deviates to relate to H3N2 disease.
This reduction was statistically significant for peak assays with saline and ADP 8×10 −6 M, nearly significant using tissue factor 1 pM, and non-significant using arachidonic acid 25 mmol/L.
paracasei showed nearly significant correlations with lactate (adj. p-value 0.064 and 0.094, respectively).