“near-significant”

This analysis detected a near-significant association between the genomic region encompassing bicaudal D homolog 1 ( BICD 1) and emphysema severity. 109 BICD 1 is associated with dynein function and telomere shortening.

However, when these SNPs were tested in the Follow-up group for replication, only three, PIP4K2A , FTO , and rs3846601, demonstrated significant or near-significant associations with consistent effect directions.

The near-significant result for religious affiliation, particularly the higher satisfaction among Protestants, compares with the findings from Ghana where Muslim respondents were more satisfied than other religions [ 25 ].

Objectively measured PA showed no significant effects in either intervention group, except for a near-significant MVPA increase of 107 min/week [95% CI: 4; 209] over time in ExG.

This effect was probably due to higher delta values for stimulation of the front legs compared that of the antennae, although the posthoc comparison was only near-significant due to multiple comparison correction (Tukey HSD test, p = 0.047>α corr = 0.025).

Furthermore, go- relative to no-go training to alcohol caused a near-significant increase in a psychophysiological index of approach motivation (frontal EEG asymmetry) to alcohol pictures ( Bowley et al., 2013 ).

For instance, having an uncooperative spouse (B = 2.290, p = 0.055) showed a near-significant positive relationship with work-family conflict, indicating that spousal support (or lack thereof) might still play a role in conflict levels.

Firstly, BPA-treated female offspring displayed a near-significant increase in time spent in the center zone of the OFT, indicative of decreased anxiety-like behavior.

The number of CD8 + T lymphocytes increased to a significant degree in the draining lymph nodes of animals treated with XRT alone, and to a near-significant degree in animals treated with combination therapy ( Figure 3(c )).

A study conducted by Kasliwal and Deutsch [ 18 ] reported a significant and near-significant increase in the trend of IL and LL, respectively, after TDR using Charité and Activ L artificial discs with a follow-up time ranging from 12 to 24 months.

Trend analysis indicates no significant change from 1999 to 2006 but suggests a moderate, near-significant increase from 2011 to 2018.

The p-value for PSQI (0.375) suggests no significant difference in sleep quality scores between addicted and non-addicted groups, but the near-significant p-value for bad sleep prevalence (0.057) suggests a trend toward worse sleep among the addicted group.

However, the near-significant association of time to ART initiation with neutralization, while not reaching statistical significance, suggests a potential but less pronounced role of early ART initiation in shaping neutralization responses.

In particular, our (near-significant) results regarding the analysis of adjuvant systemic treatment, as well as those of the separate analysis of subcohorts with different counts of treated metastases, could both benefit from larger sample sizes, in order to clearly define the potential influence of these factors on PFS and OS.

Importantly, the strong correlation between class 1 integrons ( int I1) and flo R, alongside near-significant associations with cml A and ere A, reinforces the role of integrons as major drivers of multidrug resistance dissemination in poultry-associated Salmonella .

Donepezil (0.1–1 mg/kg) showed near-significant enhancements in d ′, and EVP-6124 (0.3–3 mg/kg) exerted no effects in the rCPT paradigm.

Overstated claims and misleading trends (e.g., near-significant findings) have been corrected.

Descriptive tests between the experimental and demographic measures revealed a trend in correlation across participants between age and MWP score (Pearson’s r = − 0.38, p = 0.058), suggesting a near-significant decline in mindwandering tendency with advancing age [ 23 ].

The 2015–2019 rise, though less pronounced than among females, suggests challenges in high-risk male groups, such as migrant laborers, with the near-significant decline in 2019–2021 indicating partial mitigation efforts. 4 Forecast Results: Projected Age-Standardized prevalence Rates of Latent Tuberculosis infection in South Asia, 2021–2050 Projections of age-standardized prevalence rates (ASPR per 100,000 population) for latent tuberculosis infection (LTBI) in South Asia and its five constituent countries were generated using auto-ARIMA models fitted to Global Burden of Disease (GBD) 2021 historical data from 1990 to 2021, with forecasts extended to 2050 accompanied by 95% prediction intervals (95% PI).

Here one should draw a profound distinction between the illegitimate procedure of uncorrected p-hacking on a completed dataset and the valid procedure of post hoc sample incrementing to bolster near-significant results.

Disentangling this latter interaction further, we found that it was due to near-significant differences at fronto-central locations between the familiar and novel stimuli before training, showing larger amplitude for the familiar items [F(1,10) = 4.2, p = 0.068, R 2 = 0.296], whereas after the training the amplitude for the novel items increased and this difference was obliterated [F(1,10) = 0.60, p = 0.811].

To aid interpretation of this near-significant result, exploratory pairwise Wilcoxon rank-sum tests were conducted.

However, the interpretation of these near-significant findings should therefore be made with caution, constrained by the very small number of valgus knees in the postoperative cohort, which limits meaningful alignment-based subgroup comparisons.

While none of the OTUs were statistically significant ( p FDR < 0.05; see Additional file 3 : Table S5a), two out of the three near-significant OTUs ( p FDR < 0.10) in the meta-analysis were also discovered in our original analysis.

Significant or near-significant differences in levels of various health behaviour were found between those who used recommended vaccinations and those who did not.