“near-significant”

22 months, p = 0.01), and OS showed a near-significant improvement (63 months vs. 52 months, p = 0.05).

In separate analyses of each outcome variable, the interaction term was significant or near-significant in all four cases (chocolate: B = 0.93, 95% CI −0.01–1.87, t = 1.95, p = 0.05; crackers: B = 1.22, 95% CI 0.35–2.09, t = 2.78, p = 0.006; crisps: B = 1.43, 95% CI 0.57–2.28, t = 3.31, p = 0.001; popcorn: B = 1.25, 95% CI 0.29–2.21, t = 2.58, p = 0.01).

However, despite no moderation effect, the temperamental characteristic of IBQ distress to limitations had a near-significant main effect in the 6 months (β = 0.28, p = 0.05), 9 months (β = 0.27, p = 0.06), and 12 months (β = 0.28, p = 0.05) models.

Two-tailed independent sample t-tests revealed significant or near-significant between-group differences at Time 1 for network strength (p = 0.05), number of links (p = 0.046), mean correlation coefficient between nodes (p = 0.04), clustering coefficient in the TBI sample (p = 0.06) and small worldness (clustering/path length) (p = 0.062).

The regression model included variables that had a significant ( p < 0.05) or near-significant (0.1 ≥ p ≥ 0.05) association with likely high stress and low resilience in the chi-square test/Fisher’s exact test analysis.

A 4 (gravities) x 4 (distances) repeated-measures ANOVA confirmed main effect of gravity, F (4, 240) = 16.56, p < 0.01, main effect of distance, F (3, 240) = 67.47, p < 0.01, and near-significant interaction, F (12, 240) = 1.79, p = 0.05.

There was a near-significant difference between PD-NC and PD-MCI in the FPCN-VN connectivity, which was higher in PD-MCI ( p = 0.05, p ˆ = 0.75); see Fig. 2 a-c.

Higher English language proficiency (β = 2.60, p < 0.001) and age (β = 0.24, p = 0.018) significantly contributed to higher MSPSS scores, while duration of residence in Canada had a near-significant effect (β = −0.05, p = 0.050). 3.3.

There was a near-significant interaction between salience and self-investment, F (1, 60) = 4.01, p = .050, η p 2 = .06.

Variables showing significant or near-significant associations ( p ≤ 0.05) were subsequently included in multivariate models to adjust for potential confounders, including adiposity indices (BMI SDS, WHR), biochemical markers of metabolic syndrome (HDL cholesterol, triglycerides, insulin), cranial radiotherapy exposure, and the number of pituitary deficiencies.

However, we did identify a near-significant ( p = 0.050) association between the presence of a solid growth pattern and low-risk tumors.

The remaining near-significant differences ( P > 0.05) in fatty acid concentrations were found during and after the WW event.

Other near-significant results, such as for FD_AP in Trial 2ec ( p = 0.05, r = −0.28) and FD_AP in Trial 2eo ( p = 0.06, r = −0.27), also hint at increased complexity in sway among addicted individuals, though they did not meet conventional significance thresholds.

Additionally, a near-significant reduction in FC between FP-2 and VIS-1 ( F = 4.140, p = 0.050, uncorrected) indicated a trend toward diminished FP–visual network FC in PD-CD relative to PD-ND patients. 4 Discussion 4.1 Key findings and contributions In this study, we developed a multimodal ML model that integrated structural (gray matter volume, GMV) and functional (resting-state functional connectivity, FC) MRI data with minimal clinical parameters to distinguish PD patients with beginning cognitive deficits (PD-CD) from those with normal cognition (PD-ND).

Overall evidence shows no clear sleep improvement (SMD = −0.12, 95% CI: −0.37, 0.12, p = 0.32), despite borderline significance in the high-adherence subgroup ( p = 0.05) and near-significant subgroup differences ( p = 0.06).

Belimumab prevented mcBILAG flares to a greater extent than placebo in patients with positive anti-dsDNA levels (HR: 0.70; 95% CI: 0.50–0.98; P = 0.035) and with a near-significant separation in patients with baseline SLEDAI-2K ≥10 (HR: 0.71; 95% CI: 0.51–1.00; P = 0.050), whereas no difference was seen in their counter groups.

Pertussis vaccination also had a significant increase from 40,4% to 66,1% (chi-sq 7,1, p = 0,008), and measles vaccination had a near-significant increase from 85,1% to 96,6% (chi-sq 3,7, p = 0,05).

Focusing on studies reporting between-subject correlations (619 men and 1,059 women), there was a near-significant association between the average sample age and subjective-genital agreement for men, r (20) = .42, p = .05, and a small and non-significant association for women, r (42) = .18, p = .25.

In the same data set, patients with high levels of miR-197 showed a near-significant (P = 0.0501) decreased survival compared to miR-197 low patients (Fig.

The anti-inflammatory cytokine, IL-10, appeared also to be secreted at lower levels, to a degree that was near-significant ( p = 0.0503).

When AYA patients were stratified by SIL spatiotype regardless of ICI outcome, the SIL high group showed a trend of longer OS and a near-significant longer PFS ( P = 0.0504) compared to SIL low group (Supplementary Fig. 5f, g ).

However, favorable trends were observed in arousal-related metrics, with a near-significant decrease in arousals (–34 events; p = 0.0504) and arousal index (−5.0 events/h; p = 0.0833).

Regarding biomarkers of liver function, levels of total bilirubin, direct bilirubin and indirect bilirubin were unaffected by walnut consumption, although an increasing trend in total bilirubin and indirect bilirubin was observed in participants regardless of their group with a near-significant main effect of time ( p = 0.0505 and p = 0.0729), suggesting that academic stress may lead to a mild increase in total bilirubin levels.

There was also a near-significant decrease in VEGF levels in placentas from treated animals compared to those from control animals (34.78 ± 2.36 pg/mg vs. 41.99 ± 2.47 pg/mg, respectively; p = 0.0505) (Fig. 4b ) and a significant decrease in plasma free VEGF, which is VEGF unbound by sFlt-1 (1174 ± 38.45 pg/mL vs. 1492 ± 62.25 pg/mL, respectively; p = 0.0006) (Fig. 4c ).

Oleate increased the expression of the LEP gene approximately three-fold compared to controls and was near-significant ( p = 0.0506).