“near-significant”

STH infection was a significant negative predictor of IgG1 galactosylation, and schistosomiasis and CRP level near-significant predictors.

However, we overcame this by including only factors that showed significant or near-significant associations in preliminary bivariate tests.

Additionally, in the present study, tumour dimensions may be more closely associated with therapeutic resistance than with therapeutic sensitivity, as there was a near-significant association between BSLD and PFS.

Although they are not statistically significant, higher education level (B=-0.427, p=0.062, OR=0.652) and higher monthly income (B=0.237, p=0.105, OR=1.268) showed near-significant trends, which suggest that there is a possible influence of these parameters on QoL of collagen users.

(4b) Likewise, the MR analyses have only a very weak statistical signal (p=.02,.03): 1 this doesn't survive correction for testing two phenotypes (not to mention the implicit tests prioritized by rhog that were discarded based on LCV); 2 the LCV paper proves these tests are susceptible to inflation by genetic correlation; 3 I do not agree that horizontal pleiotropy has been ruled out, a priori it seems almost certain that many heritable traits (BMI, smoking, diet, exercise,....) will causally effect both glucose and lung function, to some extent, and moreover you do show that AMT has near-significant TWAS effects on both smoking and glucose.

1G , plasma insulin levels measured from samples collected 10 min into the last IPGTT experiments displayed a near-significant tendency to be reduced acutely but increased at 6 hours after exendin-4 treatment for β-arrestin 2 KO versus control mice when normalized to their corresponding vehicle values (fig.

By contrast, there were significant or near-significant decreases in the value of k 1 in active treatment vs control groups in each trial, and a significant decrease in the average k 1 across the trials ( Table 3 ; control k 1 = 0.030 ± 0.004 vs active treatment k 1 = 0.016 ± 0.003, p < 0.01).

However, there was a near-significant effect in the requests subscale, suggesting a possible trend that could be explored with a larger sample size.

IL-1β and TNF-α showed a significant or near-significant decline from 5 to 24 h following cooking and candle exposure compared to clean air exposure (Table 2 ).

Consistent with the known anti-inflammatory effects of weight loss [ 25 ], VLCD-induced rapid weight loss resulted in decreased levels of hsCRP, reduced white blood cell count, and a near-significant reduction in circulating IL-6 levels [ 26 ].

Cyanocobalamin supplemented at 1 μg/mL (750 nM) did not increase the cell number in homocystine-treated HCT116 and MC38 cells ( Figure 1 A,B), and a small near-significant increase in CT26 cells was observed ( Figure 1 C).

Last, the limited sample size means that any significant or near-significant findings may simply reflect a chance finding; only 300 participants had available data for the global analysis assessed using the Wei-Lachin test.

Our analyses produced similar results to the combined analyses; the only significant result was a reduced risk of ALL in the 10–14 years since first use category, with a near-significant reduced risk in the corresponding category of lifetime years of use; however, these were based on small numbers, and there was no evidence of a trend in either variable.

Furthermore, we found a near-significant inverse association between ΔWSDSbirth to 3 months and insulin sensitivity (SI derived from IVGTT) and a near-significant positive association between ΔWSDS birth to 3 months and fat mass ( Table 2 ).

Interestingly, while no statistically significant predictors were found for the future perspective subscale, the near-significant negative association of chest pain invites discourse about the interaction between unresolved physical symptoms and patients’ psychological well-being.

Non-RdRp sequences that share near-significant similarity with RdRp are also characterized.

Greater variance was explained by BRIEF BRI Inhibit in the CYA-SCD-SCI+ (22%, p = 0.058), although near-significant. 4.

In turn, the findings of a near-significant association between parental “normal vision” and reduced SR willingness indicate that parents without VIL may perceive a higher risk or burden associated with another child, potentially yielding reluctance toward fertility ( 28 , 29 ).

Interestingly, we found that in addition to causing increases in amino acids that shuttle nitrogen out of tissues (alanine, glutamine, and proline), chronic treatment with tirzepatide also led to near-significant increases in levels of urea cycle intermediates (citrulline and ornithine) in BAT.

G3P elevation, together with a near-significant DHAP reduction, indicates disruption of this pathway.

Interestingly, although on average approach-related positive affect decreased after the non-appetitive mood induction procedure, there was a near-significant increase for individuals high in anticipatory pleasure.

Notably, the subgroup of patients without dialysis and with treatment > 30 weeks had a near-significant increased risk of hyperkalemia compared to placebo (pooled OR = 1.28; 95% CI: 0.99–1.65; I 2 = 0.0%) but not compared to ESAs ( Figure 13 c).

Although the individual consistency of object neophilia has not been demonstrated in Darwin’s finches, previous work in this study population found a near-significant positive among-individual correlation between object neophilia and exploration of a novel environment—which is itself a significantly repeatable trait [ 49 ].

Over the study period, predominant use rose significantly in the UK and the USA, while there was a near-significant decline in Canada and Australia was flat.

However, even with this reduced power, the QTL map for pA suggests that the genetic architecture for triglyceride level is different between the two mapping panels, as there is no evidence of near-significant peaks in pA within QTL intervals statistically identified in the pB panel (Figure S15).