“near-significant”

placebo and showed a near-significant reduction in the primary composite of total HF hospitalisations and CV death (RR 0.79, 95% CI 0.62–1.01, p = 0.059), driven by fewer total HF hospitalisations (RR 0.74, 95% CI 0.58–0.94, p = 0.013), with no difference in CV death (HR 0.96, 95% CI 0.70–1.32, p = 0.81) [ 56 ].

Similarly, disease recurrence was associated with better EFS, with a near-significant difference ( p = 0.059).

Calendar year showed a near-significant independent association with mortality after adjustment (adjusted OR 1.43, p = 0.059), suggesting that factors beyond disease severity classification are contributing to worsening outcomes.

The results using alternative measures of vigilance were similar, with only the the 4-region RH cluster showing significant (variance RT p = 0.01) or near-significant results (median RT p = 0.059).

Pairwise analysis showed a significant difference between estrus and diestrus samples (Fs = 5.29, p = 0.002) and a near-significant difference between metestrus and diestrus samples (Fs = 2.28, p = 0.059).

(g) HF: From MR–M1, there was a near-significant increase of 678.63 ms 2 (SE = 344.48, p = 0.059).

Although the change was not significant, phosphate levels in the pigs who consumed hLZ-containing milk showed a slight, near-significant increase (hLZ/control median ratio, 1.117, P = 0.059).

There were near-significant trends for ICAM-1 ( P values = 0.059) and IP-10 ( P value = 0.061).

This is in accordance with the near-significant higher apparent sodium digestibility in the CD1 mice (70% vs. 63% in C57Bl/6 J; p = 0.059) and the higher urine pH in CD1 mice found previously 41 .

Dup: p = 0.045), with dupilumab achieving a near-significant reduction (median −0.7 pg/mL, 95% CI: −1.5, 0.0, p = 0.059).

p-value = 0.0109) and near-significant downregulation of Cyp3c3 (adj. p-value = 0.059) in the brain suggest that these enzymes play a compensatory catabolic role in regulating retinoic acid levels in the absence of Cyp1b1.

Near-significant predictors of time to major ipsilateral stroke included age older than 65 (HR 2.20, P = .059), aneurysm dome depth (HR 1.06, P = .075), and dome height (HR 1.05, P = .103).

RR showed significantly higher recurrence rates when controlled for age and follow-up time compared to OR, ( p = 0.027), while LR showed near-significant higher rates ( p = 0.059).

The right peroneus longus exhibited a near-significant difference in the propulsive phase ( Figure 1 b, p = 0.059).

All 3 groups of riders made an increase in lateral movement between sections 4 and 5 in response to the hazard ( p <0.001), but the advanced riders displayed less lateral movement than the experienced riders ( p <0.05) and demonstrated a near-significant difference when compared to the novice riders ( p = 0.059).

There was a near-significant effect of drug treatment on the incidence of the tonic phase of GTCS (χ 2 test for trends (3.561,1, p = 0.0592), Figure 5 C1) driven by the effect of the highest dose of 10 mg/kg.

In BLA, opioid-experienced rats showed a near-significant increase in heroin-induced Fos relative to naïve rats (5B; main effect of opioid experience: F (1,25) = 3.893, P = 0.0596; η p 2 = 0.1347), with no main effect of rearing group (Fig. 5B ; F (1,25) = 0.6029, P = 0.4448 ) .

Several biomarkers demonstrated near-significant trends including IL-5 (OR 0.57, 95% CI: 0.22–1.02, p = 0.0597) and MDC (OR 0.49, 0.08–1.26, p = 0.144) but did not reach statistical significance. 4.

This difference was significant at T1 ( U = 83, p = .04, ES = 0.37), and similar and near-significant ( U = 89, p = .06) for the overall protocols and protocol VP3.

Heat treatment showed a near-significant effect (Pillai’s Trace = 0.13, F(6,174) = 2.1, p = 0.060, η 2 = 0.07), suggesting a moderate contribution to compositional variation at this stage.

Nevertheless, AAV5 showed a near-significant difference ( p = 0.06) ( Table 2 ), with the model indicating higher median anti-AAV5 NAb titers in the invasive group compared to the non-invasive group.

In the 40 Hz tVAS group, attention showed a near-significant improvement ( p = 0.06), and TS 1 and 2 exhibited significant improvements compared to baseline values.

Training duration also predicted some of the distant outcomes: Vocabulary (partial r 2 = .09, p = .02) and Raven's Advanced PM, although only at a near-significant level (partial r 2 = .06, p = .06).

Post-operatively, there was a near-significant negative (B: − 0.52; OR: 0.60 [0.35, 1.02]; p = 0.06) association with lower IWB scores and time spent on social media.

[ 24 ], a near-significant reduction in current pelvic pain associated with "Physio-EndEA" was also observed after the intervention (-1.63 [-3.66, 0.02]; P = 0.060).