“narrowly missed statistical significance”

At 16 weeks after hair tonic usage, the mean anagen hair rate was even more improved, by 5.7% compared to baseline, but narrowly missed statistical significance ( P =0.1172).

However, external root resorption demonstrated a clear age trend, being more frequent in the 31–45 group compared to both younger and older patients, though the difference narrowly missed statistical significance [ χ 2(2) = 4.28, p = 0.118]. 3.5.

Compared to the minimally affected 2 MBq group, the 1 MBq group had significantly lower survival ( p = 0.0042), although it narrowly missed statistical significance compared to the 3 MBq group ( p = 0.808).

During the 24-week trial, only the 30 U group separated from the control group, but the numerically superior improvement narrowly missed statistical significance at the primary endpoint [ 21 ].

While none of the 1463 Reactome pathways were significantly enriched for DC differential expression (corrected p -value at 0.05), two pathways were significantly enriched for AC (Platelet sensitization by LDL and Response to metal ions), three for TI (Cytoprotection by HMOX1, Haem signalling and Response to metal ions), and one was significant for R (Aflatoxin activation and detoxification), and four narrowly missed statistical significance, including two interferon signalling pathways—gamma and alpha/beta (corrected p -value at 0.059, Supplementary Fig. 7B ).

However, after adjustment, fast food consumption and frequency of exercise narrowly missed statistical significance.

For example, the change in NT-proBNP narrowly missed statistical significance and was in the direction of benefit, consistent with other trials of SGLT2i in nondialysis populations.

Regarding demographic factors, although the p ‐value for gender ( p = 0.053) narrowly missed statistical significance in our multivariate analysis, we retained it due to its strong clinical relevance.

While this narrowly missed statistical significance, it is a striking observation that should be further explored in a larger cohort.

The difference in general caregiver burden narrowly missed statistical significance, which may indicate a trend that could be attributable to the limited sample size.

The effects only narrowly missed statistical significance for dichotomous data.

The reduction in risk of a decline in eGFR associated with coffee consumption narrowly missed statistical significance in participants with a long duration of diabetes (≥15 years) versus those with a shorter duration, but was significantly larger in participants with poor glycemic control (baseline HbA 1c ≥8%) than in those with better glycemic control.

Although β-alanine narrowly missed statistical significance after multiple testing correction ( q = 0.056; Table S8 ), the trend was reproducible across all experiments ( Fig.

83.2%; RR = 1.05; 95% CI: 1.00–1.10; p = 0.054) that approached but narrowly missed statistical significance.

Apabetalone, a bromodomain (BRDU) inhibitor, has recently been tested in a large phase III clinical trial and the results only narrowly missed statistical significance [ 54 ] (updated findings were disclosed in AHA-2019).

83 Our microarray data also revealed decreased SHH expression in day 40 CDH LOs, but this narrowly missed statistical significance.

Nonetheless, absolute islet mass also rose 30% in both treated groups although the increase narrowly missed statistical significance in shams due in part to variability within the group (4 animals did not have values greater than the mean of controls while 3 were markedly increased).

Female sex was significantly associated with worse survival in the univariate analysis but narrowly missed statistical significance in the multivariate analysis.

TSA crossed the monitoring boundary under the selected assumptions; however, because the conventional meta-analysis narrowly missed statistical significance and TSA is sensitive to assumptions regarding anticipated effect size and control event rate, this finding should be interpreted cautiously and considered exploratory ( Figure 10 ).

control comparisons), the t -tests comparing the RTs of OL, TE , and RB position groups to those of controls narrowly missed statistical significance, whereas the RT comparisons between each of the five remaining position groups ( WR, QB, DL, LB, DB ) and controls were statistically significant.

All other subscales showed moderate correlations but narrowly missed statistical significance.

We also included Cyp6P3 in the analysis as a strong pyrethroid metabolizer that narrowly missed statistical significance in one of the four comparisons, in addition to the other known strong metabolizer, Cyp6M2 , even though this was not consistently differentially expressed.

As a sensitivity analysis, we also fit a model containing all candidate predictors without prior selection (Supplementary Table S2); effect estimates were consistent with the main analysis in direction and magnitude, although frailty narrowly missed statistical significance in the full model (aOR: 0.72, 95% CI: 0.51 to 1.02).

3 In PARAGON-HF, which enrolled patients with HF and preserved ejection fraction, sacubitril/valsartan narrowly missed statistical significance for its primary end point. 4 However, a subgroup analysis suggested potential benefits in subjects with below-normal left ventricular ejection fraction.

miR‐34c was substantially higher among dogs with mammary carcinoma than healthy subjects, although this difference narrowly missed statistical significance (Figure 4B , Table 2 ).