Disadvantageously, dropped variables cannot be re-entered into the model, even though they might be significant in later iterations [ 87 ], but in comparison to forward selection or stepwise models, backward selection does not require strict preselection and can better identify useful combinations of predictors without requiring individual explanatory value of each variable.
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Mobility difficulties and other disabling and unpredictable symptoms might be significant barriers for people with MS accessing face-to-face services.
So there might be significant ones published and then there’d be the question of we would then potentially look at our policy and how we might want to develop our policy based on those.” (DPH04) Engagement with research outside decision-making PHPs frequently engaged with systematic reviews and other research outside decision-making processes.
Damage to PCM1 might be significant to neuro- and glio-degeneration after HI because PCM1 organizes the cytoskeleton and is critical for dendrite stability and neurite elaboration [ 129 , 130 ], possibly driving the collapse of neuronal dendrites and destruction of oligodendrocyte processes and myelination after HI.
It is conceivable that the recruitment of this domain combination might be significant to the pathogenic lifestyle.
In addition, men control economic resources that might be significant for HIV prevention and care.
While not huge, these improvements at concentrations between 200 and 500 mM might be significant if they occurred in plants encountering salt challenges in the environment.
For example, there might be significant amount of patients with isolated polycystic ovarian morphology, signs of hyperandrogenism, or un‐ovulation, in control group.
Our data point to an unexpected heterogeneity in the podoplanin-positive cardiac cell compartment, which might be significant for the processes of CLV growth after injury, development of fibrosis and scar maintenance.
Extending the leukemogenesis model of MPAL, we deduced that genetic lesions might occur at an earlier HSPC stage in adult T-ALL, resulting in abnormal proliferation/differentiation/apoptosis of myeloid and lymphoid lineages, which might be significant in explaining the difference in prognosis and treatment responses observed between pediatric and adult T-ALL ( SI Appendix , Fig.
The potential effect of targeted programs for pregnant WIDU addressing the prevention of vertical transmission of HIV, providing comprehensive assistance in treating drug addiction, and creating social conditions allowing discontinuing sex work might be significant in terms of improved health status of newborns and mothers and prevention of further spread of HIV and other blood-borne and sexually transmitted infections.
Moreover, nuclear-specific localization of the ARV7 protein within the CTCs might be significant in terms of guiding treatment selection in mCRPC patients [ 20 , 21 ].
In future research, blocking other regulatory pathways of autophagy-like mTORC1 might be significant, including AMPK upstream and downstream regulations.
However, patients with lower CD4 stromal expression had better DSS ( p = 0.08), and the survival plots showed a curve deviation, which suggests that the results might be significant in the case of a larger study group ( Figure S1 in Supplementary Data ).
Knowledge of the influence of different conditions on dehalogenation might be significant in improving the process.
The short operative time might reflect the ease of this technique, and this might be significant in an economical context.
We did this because 1) both groups operate outside the industry per se, meaning their interest is not first and foremost advancing profits and sales, but instead offering agricultural information relevant to cranberry growing; and 2) both groups publish monthly newsletters addressed to growers—affording us a second method with which to understand how social ties to these two organizations might be significant in shaping climate attitudes among their readership. 2 The use of this “mixed methods” approach helps add validity to the findings that are achieved in one analysis by allowing for results to be compared to those of a different, yet complementary, method of inquiry (Hesse-Biber 2010 ).
This approach surpasses the deficiencies of previous architectures that required Bonferroni correction for false rejections and returns additional as well as weak associations that might be significant.
We speculate that the subcarinal node might be significant as a common path where the lymphatic channels from various organs in the thorax meet, either directly or by means of lymphoid relays [ 27 ].
In contrast, individual spiny cell axons mostly contact the proximal, medial or distal parts of the dendritic tree of other spiny neurons [3] , [6] , [23] – [28] , [37] , so here delay might be significant.
In blood pressure research , American Heart Association (AHA)/American College of Cardiology (ACC) 2015 guidelines recommended a target for blood pressure below 140/90 mmHg in stable or unstable coronary artery disease patients and below 150/90 mmHg in patients older than 80 years of age, however the recent results of the Systolic Blood Pressure Intervention Trial (SPRINT) trial have suggested that there might be significant benefits, taking into account cardiovascular risk, for hypertensive patients over 50 without diabetes and blood pressure levels <120/80.
Potential reasons for this phenomenon might be significant integration of China into the global value chain since its accession to the World Trade Organization.
As a result, cN2 is a poor prognostic factor in the tumor center, and CD66b and CD15 alone could not predict prognosis, as only the univariate analysis suggested they might be significant markers.
These need to be included in a regression model, as they might be significant confounders.
Background Pilots' physical and mental health might be significant contributing factors to flight safety.