“may be significant”

[ 26 ] reported that overexpression of EP2 receptor in neoplastic tissue exerts tumour cell activity and that it may be significant in the aggressive behaviour of oesophageal squamous cell carcinoma.

In this respect, the role of nibrin in both DNA repair and cell cycle regulation may be significant.

This pattern may be significant because basal and lateral adhesion signaling are coordinated through multiple pathways to promote or inhibit cell migration [ 56 ], suggesting a possible role for CLCA2 in cross-talk between AJ and hemidesmosomes.

Furthermore, since multiple comparisons were made (six factors were tested for each of the eight cancers), some tests (two or three) may be significant by chance.

Although the difference was insignificant the sample size of the present study and that of the above-mentioned studies, it may be significant in a larger sample size.

Other factors may be significant but could not be detected in a sample of this size.

The cumulative effect of these methodological problems means that there may be significant overreporting in ad hoc cross-sectional studies.

However, it may be significant that an isoform of CD133 specifically associated with stem cells was found in cells of the basal layer of human neonatal epidermis, and coexpressed there with integrin β-1, which is also expressed by hHpSCs and hepatoblasts.

Study results were considered statistically significant if the p -value was < 0.05; however, some results may be significant by chance.

There may be significant differences in scope and scale between different models used in systems biology.

The results indicate that changes in certain subfields of the hippocampus and peripheral TIM-3 levels may be significant factors in the cognitive decline of individuals with KOA.

For instance, small molecule ISRIB can reverse the effects of eIF2α phosphorylation on translation and regulate the dynamics of stress granules, which may be significant for treating diseases associated with eIF2α phosphorylation, stress granule formation, and cognitive decline [ 134 , 135 ].

There may be significant differences in neurovirulence SARS-CoV-2 variants circulating during the periods.

Positive hits based on a single read may be significant and should be investigated, depending on the coverage level and other criteria. • Could NGS be used in combination with a previous step of cell culture for enrichment? o Blandine de Saint-Vis indicated that it could be done but it would require a cell sensitive to all viruses and monoclonal antibodies to neutralize the virus from the vaccine, so this is a challenge.

This finding may be significant as acute alcohol consumption has been shown to suppress parallel fiber long-term depression in the cerebellum, which may contribute to alcohol-induced deficits in motor coordination in rats [ 54 , 55 ].

Primarily asexual reproduction coupled with periodic sexual outcrossing may be significant for the adaptive evolution in novel environments and may be particularly important for invading urbanizing environments where rapid adaptation may be at a premium.

It is also necessary to consider the influence of polymer treatment on the results, as polymers are susceptible to processing history and every step, from polymer preparation in granular form to diluting it in different solvents, casting and drying in different conditions, may be significant to a final outcome.

We particularly emphasize that benzene and naphthalene may be significant risk factors, mostly due to their high toxicity (benzene and naphthalene have CPFs of 0.1 and 0.12, respectively), as well as their widespread sources and significant emissions.

Understanding their translation may be significant to the chosen timing of energy demanding interventions to improve function and health.

The distortion is probably small in many cases but may be significant enough for professional sports like darts, golf and baseball where each throw or hit significantly influences results.

Vibrios have been shown to be associated with Artemia in previous studies using culture techniques [ 10 , 12 - 14 , 37 ] and may be significant to the Artemia life cycle as a symbiont or pathogen.

First, this was a population-based cross-sectional survey with self-reported questionnaire, and thus, there may be significant recall bias.

Despite global gains in addressing child marriage, including a decline from 25 to 21% of young women married under age 18 in the last decade [ 1 ], research suggests that there may be significant within-country variation due in part to contextual factors that accelerate vulnerability for girls.

Based on inverse proportions of eosinophils, macrophage numbers also appear to be higher in the granulomas of naturally-infected wild water rats ( Nectomys squamipes ) than in chronic granulomas of experimentally-infected mice ( 133 ), indicating that there may be significant differences between experimental and natural granuloma formation that must be taken into account.

Thus, even without the UTX mutations, anomalies affecting UTX expression levels such as haploinsufficiency and DNA methylation in the promoter region may be significant contributors to cancer formation 9 .