“may be significant”

Thus, the cell experiences oxidative stress and there may be significant protein degradation and lipid peroxidation in the cell membrane ( 20 ) .

This may be significant in the design of selective ADAMTS inhibitors, such as cis -1( S )2( R )-amino-2-indanol-based compounds.

Notwithstanding potential limitations with case definition, previous studies conducted predominantly with Caucasian, Hispanic and Black populations have estimated the prevalence of lupus arthritis to vary widely between 35% and 90%, suggesting that there may be significant disease phenotypic variation between ethnic groups [ 23 ].

Although the second change probably does not entail a significant functionality effect, the TalpHex-T1 E74G instead may be significant.

the saccade TRF has a significant time point) or we may find a significant response for cuts, or the responses may be significant for both (i.e. both TRFs have a significant time point).

These observations suggested that this region may be significant for TFAP2A functions in BOFS development.

32 Though there may be significant heterogeneity between PCOS patients and patients with recurrent miscarriage, resulting in different outcomes of EPL after LMWH treatment.

It may be significant that transcription is heavily reduced in Rsc8-depleted cells ( Parnell et al. 2008 ; Hartley and Madhani 2009 ), perhaps suggesting the loss of critical components of a transcription complex, reflected by the smaller footprint.

Another explanation is that there may be significant differences between cell lines that have the signature PAX-FOXO1 fusion (SJCRH30) [18] and those that do not (RD), which would actually be an important finding because those tumors are the most aggressive and difficult to treat.

It is noteworthy that the structure of circRNAs exhibits a stable loop structure, higher resistance to RNA exonucleases, and an extended half-life, which may be significant in various cellular processes.

26 In contrast with this result, a genetic study demonstrated that appetite regulation genes may be significant markers of risk of developing obesity. 27 Further studies should be conducted to clarify the relationship between dietary intake and BMI among the MA-dependent patients.

Previous studies have suggested that an association between heaviness of cigarette smoking and SPD may be significant, but gender differences in the association are unclear.

Although the impact of hot weather on mortality is generally largest in urban environments [ 63 ], it may be significant also in rural areas [ 62 , 64 ].

One important 5-HTTLPR polymorphism feature is that the variation may be significant between different groups and/or races. 27 A strength of this study is that the association between 5-HTTLPR mutations and IBS risk is pooled only in the Chinese population.

In well-fixed preparations there may be significant steric hin- drance to the bimolecular association of a particu- lar antigen, bound within the section, and the antibody which recognizes it.

However, the Maltese group included fewer dogs than Chihuahua and Yorkshire Terrier, so the tendency to have larger kidneys may be significant in a larger cohort.

Conclusions Our results support the hypothesis that environmental insults may be significant drivers of CRS pathogenesis through epigenetic mechanisms that result in dysregulated mRNA transcription and cytokine expression.

The design of all of these masks is roughly similar, however, some differences may be significant. 4.1.

However, the accumulation in mitochondria of type of lipophilic species may not be selective towards cancerous cells, and the side effects may be significant.

To determine the site of obstruction, a large incision is usually required, and there may be significant manipulations of the bowel.

In comparison with the top 20 attributes in Figure 8 , the three selected attributes are not the top ones as calculated by correlation, which indicates that attributes of lower correlations alone may be significant when combined with others that lead to an effective cohort. 4.

Although the elevation of IOP is well-known to affect retinal perfusion (Geijer and Bill, 1979 ; Zhi et al., 2012 , 2015 ; He et al., 2013 ), the IOP during the ischemic phase of IR surgery ranges from 60 to 120 mmHg, and the reservoir height used is not standardized, meaning that there may be significant variation between investigators (Zheng et al., 2007 ; Huang et al., 2013 ; Hu et al., 2015 ; Seong et al., 2017 ; Zanoni et al., 2017 ).

This may be significant given the diverse roles of MHWs samples and multiple settings featured in included studies.

Furthermore, there may be significant behavioural differences within a family, among species of the same genus, or even among different populations of the same species ( Jones 1977 ; Singer and Parmesan 1993 ).

Thus, even without the UTX mutations, anomalies affecting UTX expression levels such as haploinsufficiency and DNA methylation in the promoter region may be significant contributors to cancer formation 9 .