However, there may be significant linkage disequilibrium (LD) between adjacent markers in dense SNP marker sets, which can lead to false positive results [ 3 ].
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In the literature
Hypersalinity is known to partially inhibit photosynthesis [ 15 ] and thus oxygen production, which may be significant given the wide range of salinities present.
Improvement of motor symptoms by MAO-B inhibitor monotherapy as first-line treatment may be poor and lead to the requirement for concomitant levodopa or a dopamine agonist in some cases, but use of a MAO-B inhibitor from the early stage may be significant for the long-term course.
Early clinical care and early prevention plan application may be significant for identifying patients who do not respond to drug therapy using these machine classifiers.
A p -value cut-off of 0.2 was used to detect variables that may not be significantly associated to the outcome in the univariate analysis and may be significant in a multiple model after adjustment of other covariates.
Results falling outside the acceptable limits may be significant as they exceed the normal day-to-day biological and analytical variation.
It may be significant that the latter gene clusters immediately adjacent to Wrky53 in the Genevestigator diagram (Figure 20 ).
However, the presence of the drug may be significant circumstantially in explaining why the individual was in the situation where he was shot, as well as for the collection of statistics concerning illicit controlled drug use in that jurisdiction.
It is also increasingly being discovered in urban green spaces such as public parks, where the opportunity to encounter and transmit pathogens to humans and companion animals may be significant [ 17 ].
Despite the fact that initial testing was conducted to determine whether there may be significant demographic differences (e.g., regarding BMI) between both groups, there may be other undetected confounding factors.
Although the biases are typically small, we demonstrate, using numerical examples, that there are regimes where bias may be significant.
Clinical significance was determined by comparing the 95% CI of the observed differences to the MCID threshold for each scale: differences were considered “clinically significant” if the lower bound of the 95% CI exceeded the threshold, “may be significant” if the 95% CI included the threshold, and “not clinically significant” if the upper bound of the 95% CI was below the threshold [ 37 ].
Conclusions This retrospective study demonstrated that FR and plasma NGAL may be significant predictors of severe AKI progression in general ICU patients.
Their study indicated that environmental stimuli regulated the activity of capsaicin-sensitive neurons innervating the dental pulp and these factors may be significant clinically in the development of dental pain.[ 11 ] Foodstuff, stress, surgery and drugs may influence salivary pH and a randomized clinical trial by Duane suggests that the use of high-dose xylitol chewing gum has beneficial effects on plaque pH and Streptococcus mutans in children at high risk for caries.[ 25 ] Many antibiotics are secreted in the saliva and may affect salivary pH (which may in turn affect PEP).[ 26 ] However, among these many contributing factors, very little, if any attention has been directed toward the relationship between salivary pH and the intensity of PEP.
In this context, the observed changes in the expression of these proteins may be significant for understanding susceptibility to E. caproni infection, particularly in relation to the development of Th1-type immune responses and a lack of responsiveness to IL-25.
The results of this study indicate that these processes may be significant enough to cause failure of ARV therapy after a few months, warranting a switch to second line ART.
Therefore, such a difference in body size between dangerous and non‐dangerous prey in small predators may indicate that the effect of capture risk on prey selection may be significant for predators.
5 , 6 Although the HOMA-IR is a static measure, it has been validated against the clamp 6 and used extensively in adolescents, with a value of 3.16 proposed as the low value, above which there may be significant IR in adolescents. 4 While the HOMA-IR provides a reasonable estimate of insulin resistance, it is rarely performed without an initial degree of clinical suspicion.
This new gluten-free approach may be significant since it allows regular beer components and recipes to be used.
This either suggests that there is no association between conventional occupations and PD or, alternatively, that this study was statistically insufficiently powered to detect a true association with a modest effect size that may be significant from a clinical perspective (i.e.
M06L 56 , 57 is a meta-GGA (Generalized Gradient Approximation) functional that includes dispersive interactions, which may be significant for the adsorption and chemical reactions within zeolitic materials.
The rise in calcium content in Reishi-enriched bread may be significant in the prevention of osteoporosis, degenerative joint diseases, and in conditions of increased calcium demand, such as menopause, periods of rapid growth, or for individuals engaged in intense physical activity [ 51 ].
Hence, the role of CBS in cell division we described in yeast may be significant for human biology.
There may be significant clinical differences between the models.
Considering that FISS is regarded as a chronic inflammation-associated tumor with histological features that are similar to wound healing, the expression of STAT3 may be significant and plays an important role in tumorigenesis.