Barely Significant
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“may be significant”

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In the literature

Improvement of motor symptoms by MAO-B inhibitor monotherapy as first-line treatment may be poor and lead to the requirement for concomitant levodopa or a dopamine agonist in some cases, but use of a MAO-B inhibitor from the early stage may be significant for the long-term course.
Clinical significance was determined by comparing the 95% CI of the observed differences to the MCID threshold for each scale: differences were considered “clinically significant” if the lower bound of the 95% CI exceeded the threshold, “may be significant” if the 95% CI included the threshold, and “not clinically significant” if the upper bound of the 95% CI was below the threshold [ 37 ].
Their study indicated that environmental stimuli regulated the activity of capsaicin-sensitive neurons innervating the dental pulp and these factors may be significant clinically in the development of dental pain.[ 11 ] Foodstuff, stress, surgery and drugs may influence salivary pH and a randomized clinical trial by Duane suggests that the use of high-dose xylitol chewing gum has beneficial effects on plaque pH and Streptococcus mutans in children at high risk for caries.[ 25 ] Many antibiotics are secreted in the saliva and may affect salivary pH (which may in turn affect PEP).[ 26 ] However, among these many contributing factors, very little, if any attention has been directed toward the relationship between salivary pH and the intensity of PEP.
5 , 6 Although the HOMA-IR is a static measure, it has been validated against the clamp 6 and used extensively in adolescents, with a value of 3.16 proposed as the low value, above which there may be significant IR in adolescents. 4 While the HOMA-IR provides a reasonable estimate of insulin resistance, it is rarely performed without an initial degree of clinical suspicion.
This either suggests that there is no association between conventional occupations and PD or, alternatively, that this study was statistically insufficiently powered to detect a true association with a modest effect size that may be significant from a clinical perspective (i.e.