Barely Significant
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“may be significant”

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In the literature

However, considering the short gestation in rats (22.5 days) and mice (19.5 days), and their consequently faster brain development, compared to the relatively long human gestation (280 days), there may be significant differences in the effect of a pharmacological intervention aimed at crucial brain-development-mediating elements such as NMDA receptors.
Eye Loss of retinal ganglion cells [RGC] is a hallmark of many ophthalmic diseases including glaucoma, diabetes retinopathy, retinal ischemia due to central artery occlusion, anterior ischemic optic neuropathy and may be significant in optic neuritis, optic nerve trauma and AIDS ( 985 ).
Sigma receptors [σRs]: biology in normal and diseased states.
J Recept Signal Transduct Res · 2016 · PMC4906365