The economic burden may be significant.
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In the literature
One possibility for the lack of efficacy of Lebrikizumab in mild asthma patients might be that IL-13 may not be the cytokine responsible for the symptoms in such a patient population, and a role for IL-13 may be significant only in more severe forms of the disease [ 103 ].
The reasons for starting the training programme are unknown, but it may be significant that 1654 saw the start of the Russo-Polish war (1654–67), as well as plague outbreaks.
The tradeoff may be significant as an evolved mechanism that prevents the over-asymmetry of a karyotype for the sake of the maintenance of chromosome diversity, and it may also be a biomechanical limit of spindle fibers.
Additionally, as this study has shown that the resource requirements of conducting RCD and similar strategies may be significant, a finding consistent with qualitative and quantitative work already undertaken in Zambia [ 21 , 27 ].
The radiative heat transfer between the surfaces of the plates is modeled on each side of the reactor, as thermal radiation may be significant. 52 Simple estimates indicate that for the optical path lengths and species partial pressures of interest in this study, gas-phase radiative heat transfer is negligible in comparison with convection and surface-to-surface radiative heat transfer.
We demonstrate that, depending on the degree of lateral PO and femoral abduction/adduction present, ME may be significant enough to lead to the exhibition of clinically relevant apparent discrepancies, even when in actuality, none truly exists.
Fourth, the diagnosis or symptom of COVID-19 of the participants may be significant moderators which was not assessed in this study.
These findings, together with our own, show that there may be significant affinity maturation in individuals with pulmonary TB.
In patient populations aspects, there may be significant demographic differences between the two databases, such as age, gender, and racial distribution.
The findings may be significant with valuable information for oncologists to better understand the role of BRCA mutations in breast cancer patients and optimal treatment of TNBC.
Within countries, there may be significant variation in the effectiveness of fortification across population subgroups and seasons (for example, between subgroups defined by sex, locality, and season).
Additionally, the development of personalized treatment strategies is essential, as there may be significant variations in the gut microbiota composition and response among individuals.
There may be significant differences in quality, 100 which affect the efficacy and safety of these products.
The study also indicates that schools as either an information source do not suffice and that other outlets, like mass media, may be significant in the distribution of knowledge through schools [ 35 ].
Conclusions and relevance The study findings suggest that decreased serum TGF-β and tubular atrophy with TGF-β immunoreactivity may be significant in cats with CKD.
Confirming this association may be significant for clinical implications, primary prevention strategies of overweight/obesity and overweight/obesity-related diseases.
The above finding clearly indicates that in the time scale of the imaging applications (usually tens of minutes to several hours), BTCy exhibits good fluorescence stability, although the chemical instability and spirocyclization may be significant factors that affect the fluorescence property of BTCy.
It may be significant that this group was relatively young compared with the other subgroups.
The precise mode of DNA binding remains to be determined for any of the large serine recombinase subfamily members, and data accumulated from several systems suggest there may be significant differences [ 23 ].
gestational age) of the pregnant women from which PBMC were obtained were not reported by Scharfe et al., and may be significant to outcomes.
The copolymerization of tested laccase solutions resulted in higher durability of their activity on the surface unit [ 26 ] and relatively higher potential, which may be significant for its future usage in construction of electrochemical cathodes [ 36 ].
There may be significant delays for pretreatment testing (which should be managed by the referring center), arranging lodging, travel time, and insurance approval, as well as leukapheresis and CAR-T slot assignment.
The serum concentration of the monoclonal paraprotein does not correlate with fracture risk, but the class of the immunoglobulin may be significant.
It is also increasingly being discovered in urban green spaces such as public parks, where the opportunity to encounter and transmit pathogens to humans and companion animals may be significant [ 17 ].