The extent to which inappropriate test orders over the range of indications for testing contribute to wrong, missed, or delayed diagnoses is not known, but may be significant based on these findings.
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In the literature
The impact of WT1-DC therapy on IPS and the relationship between IPS and the effect of chemotherapy may be significant in clarifying the relationship between immunity and cancer, and further research is expected in the future.
Fourth, different treatments may be significant confounding factors of the disease outcome and may have further complicated the statistical analysis and the conclusions of the study.
The generation of oxidized bioactive lipids is an important mechanism that connects MPO with inflammatory processes, while a heightened activity of MPO may be significant in inflammatory tissue injury ( 10 ).
Additionally, the available data suggest that there may be significant between-country differences in health-related quality of life of the same population, and the differences may even lead to changing the conclusions of economic evaluations [ 15 ].
We speculate that eGFR differences, and the presence of DM as a comorbidity, may be significant factors in differentiating spectra.
Whether these alterations are persistent or transient are poorly captured by a single test, and there may be significant discrepancy between test outcomes.
Thus, PDIA3 activity may be significant for conditioning of the TME.
This may be significant as findings from the two studies that did not exclude women with previous hypertension [ 18 , 23 ] were in opposition to those that did [ 16 , 17 , 20 , 22 , 24 ].
Due to the high variability and boundary condition dependence of bubble-fluid coupling effects, there may be significant differences in bubble behaviour between fixed and moving boundaries.
5 However, transmission by contact may be significant in case of pandemic viruses, but we will not know that with certainty until putative pandemic viruses are identified. 6 The difference between knowledge about transmission and prevention could be the result of prevention campaigns focused on standard hygiene more than on their justification.
In this regard, it may be significant that 10 transcripts, comprising 3% of characterised ESTs, were identified in lupin exudate as those for bean yellow mosaic virus polyprotein.
Based on previous exploration of the issue of the role of stress coping strategies within the PS made it possible for the authors to conclude that, at the statistical trend level, reverting to alcohol or other psychoactive substance use strategies may be significant for the development of job satisfaction of PS security staff who are responsible for order and security in a facility (questionnaire statements referred to “alcohol or other substances”) [ 13 ].
13 , 14 As a result, there may be significant potential to protect and enhance nutrient production where trophic downgrading has already occurred.
This may be significant for patients undergoing prolonged surgery and especially those with glaucoma.
However, certain clinical presentations and histopathological findings may be significant predictors of poor prognosis.
Furthermore, the impact of confounding by glucocorticoid treatment may be significant.
An evidence-based systematic review of OCS use revealed that there may be significant short-term improvements in subjective and objective measures and a strong recommendation can be made for use in short-term treatment of CRSwNP patients ( 52 ). 2.3.3.
Whether the salts are less in quantity than normal in the blood the facts do not show. It will be remarked of these blood-changes, so far as they have been matter of observation, they have been witnessed only after several days of the disease have passed. That in cases which have had some duration, the blood after death is darker and more fluid than it is customary to find it, may be significant.
The entangled AVs may be significant for both groups or for one but not the other.
In this phase, there may be significant variability of cellular appearance and atypia within the lesion, with a spectrum.
The capacity of each community to engage with this type of information will likely be highly variable, but there may be significant rewards to be realized. “Engaging the communities in a COVID wastewater surveillance project can empower citizens to identify and address needs in their communities.
Thus, housing conditions and availability of healthy social support may be significant in mitigating the effects of chronic stress.
The increased SCFAs (acetate, propionate and butyrate) were positively related to TJ proteins (ZO-1 and occludin), and negatively correlated with inflammatory cytokines (TNF-α, IL-1β and IL-6), LPS, uremic toxins (IS and PCS) and UA, indicating that SCFAs production may be significant for hyperuricemia relief by inulin treatment (Fig. 8 b).
It is also increasingly being discovered in urban green spaces such as public parks, where the opportunity to encounter and transmit pathogens to humans and companion animals may be significant [ 17 ].