7–11 With the accelerated aging of the Chinese population and changes in various UI risk factors, such as the growing obesity population and declining desire to have children, there may be significant changes in UI prevalence.
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“may be significant”
In the literature
This indicated that the steroids and steroid derivatives may be significant risk factor for ovarian disease status.
As mentioned in ( Torres-Sánchez et al., 2018 ) run times may be significant for terrestrial platforms with respect to UAV limitations.
The spat supply contribution of Ahipara, when scaled up to reflect the size of the local mussel population (large intertidal and shallow subtidal beds), may be significant, and overall more stable in the long term.
Ultimately, it has been recently suggested that the hemodynamic parameters of WSS may be significant predictors for AAA rupture risk in a multivariate analysis.
dition, PCSK9 induces atherosclerosis by increasing oxidative stress and cytokine release regardless of LDL levels.[ 17 ] In the literature, there is strong evidence that a high LDL level is related to the etiology of AS, as well as atherosclerosis.[ 18 ] Therefore, PCSK9 levels in patients with AS may be significant for both atherosclerosis and the etiology of the disease.
According to a recent expert consensus on clinical application of FDG-PET/CT in the diagnosis of infection and inflammation [ 34 ], the recommended level of FDG-PET/CT for diagnosis of peripheral OM is Level III (may be significant for clinical diagnosis and treatment), with evidence level of Level C (expert consensus, small studies, retrospective studies, and registries), while the recommended level for PJI diagnosis is Level II (which is likely to be significant for clinical diagnosis and treatment), with evidence level as Level B (single RCTs or large non-RCTs).
85 It may be significant that a quarter of DFTD tumours were found to have lymphocytes at the periphery of the tumour mass and our own observations indicate that CD3-positive cells can gather at the edges of tumours without obvious infiltration. 40 , 75 Lack of infiltration may indicate that the microenvironment is promoting tumour growth and immunosuppression (as in ref. 86 ), or these CD3 cells may be tolerogenic (i.e.
The existence of a similar PLA 2 activity phenotype, which is co-dependent on pH and temperature in both B19V VP1u and VLPs suggests that this observation may be significant in the context of the virus lifecycle.
CXCR6 is also an entry cofactor for human immunodeficiency virus (HIV)-1 [ 6 , 39 , 65 , 66 ] and HIV-2 [ 67 ] and so may be significant in the course of HIV infection.
Canonical Wnt pathway A pivotal role of Wnt signaling in physiological processes implies that its imbalance may be significant in the pathophysiology of both neurodevelopmental disorders including ADHD ( Yde Ohki et al., 2020 ) and neurodegenerative disorders such as AD ( Boonen et al., 2009 ; Inestrosa and Varela-Nallar, 2014 ).
Although research on rural patients with schizophrenia spectrum disorders is limited [ 97 ], it has been shown that there may be significant inequalities in patient care between rural and urban settings [ 98 ].
As EVs will be present in such fractions, and because EVs are known to expose proteins involve in complement activation ( 11 , 12 ), the contribution of EVs in such proteomics studies may be significant.
5 - 7 Given the apparent lack of compensatory enzyme production, the clinical implications of disaccharidase deficiency in patients with unexplained abdominal pain may be significant. 6 It is possible that disaccharidase deficiency may have been under-recognized in the United States, particularly in adults, but there has been no systematic assessment of its prevalence or symptom profiles.
Lastly, there may be significant interpatient differences in the rate of drug metabolism due to the effect of concomitant medication on enzyme function or pharmacogenomic characteristics.
Our work raises the prospect that lifestyle and environmental pollution may be significant modulators of HEV toxicity in the retina. high-energy visible light (HEV; blue light) polycyclic aromatic hydrocarbons metabolism indenopyrene (IcdP) phototoxicity oxidative stress retinal pigment epithelial (RPE) cells aryl hydrocarbon receptor (AhR) nuclear factor erythroid-2 related factor-2 (Nrf2) Natural Sciences and Engineering Research Council RGPIN-2023-04598 Fonds de Recherche du Québec—Santé This work was supported by a grant from the Natural Sciences and Engineering Research Council (NSERC; RGPIN-2023-04598) to P.J.R.
Proteins generally lie on an order-disorder continuum 21 , a description which recognizes that there may be significant intermediate stages that can have functional implications.
8 – 11 However, these scoring systems are complicated and time-consuming in clinical practice, and there may be significant inter-observer variability among the physicians who calculate these scores. 12 Moreover, there is still no single variable accurately predicting mortality in patients with AHF.
The GWAS analysis showed that DgFH18 and DgCMO-like may be significant contributors to the regulation of flowering time in orchardgrass.
Since for most methods each gene set is tested independently, there may be significant redundancy among enriched gene sets, making it difficult for biologists to interpret the results.
Recent studies have shown that deficiencies or imbalances of metal elements may be significant risk factors for diabetes and its related complications.
For this reason, the community pharmacy role may be significant in preventing this disease.
Our study, along with several other studies which reported differential NHL subtype risks for benzene-exposed workers ( 6 , 17 – 20 ), highlights the importance of assessing and reporting risk by disease subtype when possible, as there may be significant etiologic heterogeneity between different NHL subtypes.
Therefore, the model developed in this study may be significant due to its high negative predictive rate.
It is also increasingly being discovered in urban green spaces such as public parks, where the opportunity to encounter and transmit pathogens to humans and companion animals may be significant [ 17 ].