“may be significant”

The results may be significant for optimizing existing treatments and identifying novel therapeutic targets [ 18 ].

If one believes there may be significant heterogeneity of responses with a region, voxel-based analyses, such as searchlight MVPA ( Haxby et al., 2001 ), might be more appropriate to probe the target functional networks.

Of the 32% who selected an incorrect response regarding their understanding of the term “1 in 5 people...”, almost a quarter of respondents (22%) perceived that the risk meant a 5% rather than 20% risk, indicating that misunderstandings may be significant in some cases.

Although the risk of EMI from cellular phone RF energy emission on modern day devices is low, the potential clinical impact may be significant.

The absence of labeled neurons in a location may be significant, but the relative rarity of retrogradely labeled cells in L5 and 6 is of questionable validity, as this would imply that most of the reciprocity between connected areas is accomplished via the connections of L3 neurons.

A variable degree of collaterals between the RCA and the LCA develop and there may be significant left to right shunt in the survivors.

The magnitude of an observed contrast is not necessarily indicative of its statistical significance: a factor of two for climate change may be significant, while a factor of 1,000 for toxicity effects may not, partially due to the much larger range in characterization factors for toxicity.

A residual confounding may also be present, and it may be significant in cohort studies as, for example, some studies determined sunlight exposure only at baseline and/or at the end of the study.

Genotyping analyses suggest that the contribution of wild type cells to LAM tissue may be significant, to the extent that it can be challenging to detect the presence of a TSC-2 mutation at any level [ 15 ].

Their results show that the fraction of the population whose threshold doses are below an acceptable exposure level may be significant and repre- sent an upper bound on the added population risk resulting from exposure to the toxicant.

This may be significant in estimating the prognosis of seizure control after surgery.

However, in practice, while interaction coefficients may be significant, individual variables do not pass the significance test [ 61 , 62 ].

The induction of apoptosis, cell cycle arrest and a decrease in the ratios of Bcl-2/Bax protein caused by matrine may be significant matrine anti-proliferative mechanisms against cancer cells.

This indicates that there may be significant challenges related to the immunogenicity of this treatment modality [ 136 ].

Animal carers also need to consider the potential impacts of inter and intra-observer variability on scoring which may be significant when statistical methods on group data are not used to smooth out variability.

Moreover, there may be significant differences between the parents of these newly diagnosed children with ADHD and those already in the treatment and management stages of the disorder.

In addition, fish substitution or mislabelling may be significant from a sanitary point of view because of potentially dangerous toxic or allergenic substances, or else environmentally damaging where endangered species are involved (Marko et al. , 2004 ; Ward et al ., 2008 ; Wong and Hanner, 2008 ; Holmes et al ., 2009 ).

The relative importance of these 4 types of response associated with lice is not clear, but all may be significant.

If this hypothesis is true, the implications for rAAV-mediated gene therapy as a clinical option may be significant, as it may be essential to deliver rAAV.RPE65 at the time when RPE65 expression should be commencing in order to completely compensate for its loss.

The viruses belonging to the Myoviridae family may be significant contributors within the phage-bacterial network of the goat fecal microbiome, which mostly contained Bacteroidetes-Myoviridae (3.29%), Firmicures-Myoviridae (3.29%), and Proteobacteria-Myoviridae (2.79%).

Several theoretical models describing alcohol priming have explained this loss of control of behaviour following an initial prime as the result of alcohol-induced increases in incentive motivation and/or impairments in behavioural control, but are silent on what may be significant anticipated effects (e.g.

Besides, the public health implications of this dual-risk profile assessment may be significant as it could improve early intervention rates, lower healthcare costs, and enhance the quality of life among aging females especially in this population with a high prevalence of osteoporosis and CVD among postmenopausal women [ 59 , 60 ].

While the association with SD diagnosis may be significant, the effect itself may be overestimated.

This suggests that controlling SUA levels may be significant for the prevention of nephrolithiasis.

Although any level of bacterial growth may be significant for samples collected by cystocentesis, quantitative urine culture is strongly recommended because the colony count and the type of the organism identified should be considered before making a treatment decision. 4 It is important to realize that a positive culture result does not necessarily equat