“may be significant”

In this regard, the activation of AMPK by canagliflozin may be significant, as we previously identified this kinase as a potent inhibitor of EC proliferation and migration [ 71 ].

Moreover, there may be significant opportunity costs associated with regulatory and reimbursement decisions for new technologies informed by misleading findings from mapping studies.

Therefore, it is likely that the direct impact of nucleoside drugs on hematopoietic precursors, the indirect impact on the loss of endogenous function of NTs, and the altered functional consequences of nucleoside transporter variants on nucleoside analogs may be significant players in clinically observed hematological toxicities [ Figure 2 ].

In addition, the cost of purchasing the vaccine may be significant.

In addition, in this context, the method of GTV PET definition may be significant ( 29 ).

However, the impact of such cognitive deficits on day-to-day functioning is unclear, but in combination with depression, which is common in diabetes, may be significant.

As both male and female CMs and CFs have functional estrogen receptors ( 72 ), the role of this sex hormone may be significant in other primary cell models as well.

In addition, there may be significant differences between programs (see Figure 2 ) and a group of residents followed from one year to the next did not show a decline in empathy at any level of training.

Although most EV encephalitis in children have a favorable prognosis, there may be significant long-term neurological sequelae even in children who were considered fully recovered at discharge.

Discussion Recognition of cancer-specific miRNAs and their targets is critical for understanding their roles in tumor development and progression, and may be significant for exploring novel therapeutic targets.

The findings suggest that overall personality functioning may be significant in influencing individuals to adopt the protective measures recommended by authorities.

The inhibition of neutrophil apoptosis may be significant in multiple ways for the host, as it has the potential to exacerbate tissue damage but also to aid viral clearance.

This information may be significant for further guiding clinical decisions, especially in determining whether invasive procedures and treatments such as surgery are required.

The milestone assessments and competency committee decisions are relatively new, and accordingly there may be significant variation in residency program processes during this period of developmental growth in generating milestone ratings over the years of the study.

There may be significant asymmetry with the affected muscles, with muscles on one side of the body being weaker than the other.

As a result, this subject may be significant in the context of Long-COVID.

There was also a trending association with TNF-α, which may be significant with a larger study sample.

Such use may be significant in one of three ways: (i) to treat or to diagnose; (ii) to drive clinical management; or (iii) to inform clinical management.

The prospective observational study by Witt et al showed that psoriasis may be significant as a therapeutic alternative in practice 14 ; this series however involves cases that were of much greater severity and complication.

It may be significant in concussions where neuroimaging reveals no changes and indicates efficient, noninflammatory removal of microhemorrhages by the CNS tissue reaction, specifically reactive astrogliosis. 4.

Although crop N uptake is not steady and peaks particularly during mid-season shoot growth, and nitrogen leaching may be significant during these wet summer month in the EAA, the estimated net nitrification rate would be well in the range to supply sufficient N throughout the growth season for a predominantly nitrification-derived, NO 3 − -based sugar cane growth.

Improvements in specific symptoms may be significant during the study but then nonsignificant by study endpoint, further highlighting the variability in response over time.

On the other hand, our results show that there may be significant results for further research.

Since the results previously obtained in this study suggested that the early stage may be significant to the whole CI process, the genes clustered in the Black module were selected for further analysis.

Differences in performing effective intubation between the evaluated airway devices may be significant.