Barely Significant
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“may be significant”

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In the literature

The possibility of continuing visits on a fairly regular basis may be significant in accounting for the ongoing well-being benefits for people living with dementia reported by some care partners, and further research as to the factors influencing the longevity of such benefits is indicated.
In conclusion, mouse strain differences in the sensitivity to SSRI treatments were correlated with 5-HT transporter binding and reuptake in these mice, suggesting that the binding and uptake efficiency of the membrane-bound 5-HT transporter may be significant contributing factors to the marked strain differences in immobility time in the TST and FST.
Mechanisms of neurodegeneration induced by metal Aluminum (Al) Al is one of the most abundant metal elements in the Earth's crust and exposure to bioavailable Al may be significant owing to its ubiquitous presence in soil and fertilizers, cookware, and pharmaceutical and cosmetic preparations (Verstraeten et al., 2008 ).
Metal-induced neurodegeneration in C. elegans.
Front Aging Neurosci · 2013 · PMC3657624