Barely Significant
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“may be significant”

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In the literature

In India, there is still a critical shortage of ICU beds; there is an estimated need of 5 million ICU beds annually but only 70,000 are available.[ 39 ] One-analysis of Indian ICUs found that medical professionals in small hospitals managed 40% of the inpatient beds with limited facilities.[ 25 ] The potential for noninvasive ventilation to improve health care in India may be significant.
Although the exact consequence of this association remains unknown, the fact that VDBP has immunomodulatory characteristics and is responsible for transport of vitamin D metabolites supports, in theory, a model whereby the impact of reduced serum levels may be significant enough to lend itself, directly or indirectly, to the autoimmune destruction of pancreatic β-cells in the disease.