“may be significant”

2894 painmed Pain Medicine: The Official Journal of the American Academy of Pain Medicine Pain Med Oxford University Press PMC8427345 8427345 8427345 33595642 10.1093/pm/pnab069 Anxiety and Fear Avoidance Beliefs and Behavior May Be Significant Risk Factors for Chronic Opioid Analgesic Therapy Reliance for Patients with Chronic Pain—Results from a Preliminary Study Silva Marcelina Jasmine DO 1 ✉ Coffee Zhanette MSN 2 Yu Chong Ho PhD 3 Martel Marc O PhD 4 1 Founder and former Medical Director of The Focus on Opioid Transitions Program, Int

In some cases, the sample size was not sufficient, but there may be significant interethnic differences in the effect sizes at several loci; therefore, it is important to evaluate the effect of each locus in different ethnic groups [ 18 , 27 ].

7 , 8 , 9 Within and between WM lesions there may be significant differences: combined PET‐MRI analyses show substantial heterogeneity of demyelination and remyelination in voxels from the same lesion, 10 and lesions close to the ventricles exhibit greater damage compared with those in deeper tissues, 11 , 12 , 13 , 14 although it is unknown if this gradient reflects greater damage as lesions form and evolve, or a lower potential to remyelinate.

This raises the possibility that there may be significant differences in the socioeconomic status of the patients in the two treatment groups, which may have influenced the outcome in an unpredictable fashion.

From this, it can be seen that there may be significant differences in viscosity between DESs with different compositions, but their viscosity is mostly in the range of 10–5000 MPa at room temperature and pressure.

After doping with an appropriate guest, the novel EL driving mechanism is anticipated and may be significant.

Although the IS-pro and 16S rRNA analyses in our study were highly comparable, a number of practical differences were observed, which may be significant depending on the specific needs of a researcher.

This variation in sampling is noteworthy, as there may be significant differences in terms of physical and mental health between those who access shelters and those who do not [ 30 , 31 ].

Potential contributing factors include: urban stress exposure with maternal stress and immune dysregulation during pregnancy may be significant ASD risk factors [ 95 ].

There may be significant conflicts between visibility and dissemination drivers for commercial and public collections and even for separately donated materials within those resources.

2 , 11 , 12 Peripapillary sclera, composed of highly anisotropic fibers, 15 features regional variation in nonlinearly viscoelastic properties dependent on loading rates and directions 12 that may be significant for large, transient deformations during saccades. 11 Young children seldom exhibit an ON cup and virtually never ON head tilting, 43 peripapillary atrophy, or axial myopia 44 ; these features develop with age 45 and become common in myopia, 46 , 47 which is progressive and now exceeds 95% prevalen

This may be significant, given that neuroinflammation has been identified as being key in the pathogenesis of multiple psychiatric conditions including both anxiety disorder and major depressive disorders (MDDs). 9–14 Cross-talk There is evidence indicating GIT microbiota affect the functioning of luminal GIT cells, which may affect host behaviour via endocrinal signalling.

It may be significant that they belong to viral families displaying high recombination frequencies ( Makino et al., 1986 ).

Importantly, systemic IgG responses may be significant in preventing inflammation in those with IgA deficiency as a consequence of microbial dysbiosis ( 107 ).

It is known that the bioavailability of the main phytochemicals of strawberries (anthocyanins) is relatively low (often less than 1% of the ingested dose appears in the plasma or is excreted in the urine) [ 37 , 38 , 39 , 40 , 41 ]; however, its contribution to health effects may be significant.

In this line, the parameters in which the infection or the immunization occurs, such as the pregnancy stage or the maturity of the immune system of the newborn, may be significant in the production of antibodies that effectively protect against hRSV. 6.

Considering the fact that the majority of the information found by these searches on this particularly contentious health topic was inaccurate and that over half of the people who visit health websites tend to believe that the majority of the information they find there is accurate [ 13 ], it quickly becomes evident that there may be significant inaccuracies in the information that people take away from their efforts to gather information on health-related issues.

The close proximity of this area to the subareolar lymph plexus may be significant in early dissemination of tumour.

20 In addition, if multiple tooth extractions are necessary, the invasiveness of the procedure may be significant and reduce the quality of life.

It may be significant in this regard, that co-application of SUC and ATP apparently results in more durable Ca 2+ transients, conjecturing coincidence detection.

Under high EREG expression, there may be significant granulocyte chemotaxis and migration in LUSC tumor tissues, which can promote tumor growth, infiltration, and metastasis [ 78 ]; thus, affecting the immune escape and anti-tumor immune response of tumors.

Due to differences in regions and time, there may be significant variations. 4.

This may be significant also for individuals with minor mental health problems because they are at risk for developing more severe problems [ 18 , 19 ].

Previous studies have proven that the variations in the NUTCIs of the cities in the same climate zone may be significant, depending on the study scope, method, season, and background climate ( 80 ) ( Appendix E , Table E1 ).

Given that higher age did not correspond to increased complication rates, there may be significant benefits to considering CBCT for pulmonary biopsies in elderly patients.