“may be significant”

Importantly, for some patients a successful pathway to diagnosis and treatment may be short, while in others there may be significant delays leading to unnecessary morbidity and mortality.

Although large-scale prospective studies are needed to validate our findings, their clinical implications may be significant for EC management.

Although, we hypothesized that there may be significant changes in the morphologies as well as dimensionalities with respect to the solvent type and the different base concentrations, nanostructures exhibit no variations in shape and size with respect to the solvent type being water, ethanol, and toluene.

Furthermore, if one assumes that a mutagenic lesion is important for tumor initiation, then C8-deoxyguanosine substitution by these compounds may be significant for urinary bladder carcinogenesis. pmc-status-qastatus 0 pmc-status-live yes pmc-status-embargo no pmc-status-released yes pmc-prop-open-access yes pmc-prop-olf no pmc-prop-manuscript no pmc-prop-legally-suppressed no pmc-prop-has-pdf yes pmc-prop-has-supplement no pmc-prop-pdf-only no pmc-prop-su

However, retinoids are also teratogens, and there may be significant benefit obtained using ligands with defined and limited receptor specificity (reviewed in [12] ).

In the end, it seems that though concussions may be significant contributors to the national adolescent headache burden, premorbid headaches themselves may not be an independent risk factor for concussion, potentially because of greater clinician threshold to diagnosis, especially considering premorbid headaches were associated with more severe concussions.

A palliative care approach to dementia should look at symptoms across the four pillars of palliative care, but in reality, we tend to over-focus on physical and psychological symptoms, while spiritual and emotional needs can be overlooked, especially around the time of diagnosis, where such needs may be significant.

As can be seen from May and June flux values and error bars, the variation caused by spatial heterogeneity of flux may be significant, and more pronounced under conditions producing high rates of flux.

This contrasts with data from a study in Shandong, China, which suggested that high sodium intake and an elevated sodium-to-potassium ratio may be significant risk factors for MetS among Chinese adults 17 , 21 .

It is important to consider that there may be significant variations in the prevalence of COVID-19 and the response measures across different geographic locations and timeframes.

The potential survival benefit may be significant when IMA lymph node metastasis is predicted.

For samples collected by cystocentesis, any level of bacterial growth may be significant, although samples from a UTI typically contain ≥10 3 colony forming units (CFU)/mL [ 6 ].

The results showed that these samples were clearly classified into 9 different groups, suggesting that there may be significant differences in non-volatile metabolism between different groups ( Figure 1D ).

However, it may be significant that only EcArgR and VvArgR, which appear to lack α4, both have an Arg residue in α5.

This case is similar and suggests that there may be significant and potentially delayed onset of toxicity associated with dermal exposure to liquid nicotine products.

Conclusions In conclusion, our study showed that incorporation of IDC into PGG results in a change for a minority of cases, but the change may be significant in some of them.

These alterations in neural stem cell characteristics and cortical structure development may be significant for understanding ADHD’s pathogenesis and align with findings from neuroimaging studies [ 156 ]. 9.

Study Benefits The benefits to subjects may be significant.

Herein, we demonstrated that PPA location at the time of diagnosis of early‐stage PDAC and intraductal cancer extension may be significant factors in surgical planning.

Given these findings, we hypothesized that there may be significant associations between the Li response and these three circadian/clock genes ( RORA, TIMELESS and PPARGC1A ) and that these genes may be plausible candidates for this proof of principle study.

Given the step-wise increased risk of CVD events and mortality among people with elevated SBP > 115 mmHg [ 14 , 15 ], there may be significant benefits to treating prehypertension, defined as SBP 120–139 mmHg or diastolic blood pressure (DBP) 80–89 mmHg.

We found that GLS was not significantly changed at 6 months post-anthracycline follow-up; however, there was a trend towards a decrease in GLS, suggesting that there may be significant changes at a time point beyond 6 months.

Furthermore, there may be significant ceiling effects with positively framed questions, since the average tends to be so high that it is difficult to distinguish across performance levels. 17 18 The main implication of our study is that designers of patient satisfaction surveys should avoid using all positively phrased statements.

(Tracking ID #1934690) BACKGROUND: Food insecurity, cost-related medication underuse (CRMU), and housing instability may be significant, yet modifiable, barriers to diabetes management.

11 , 12 The consequences of a retained PD stent may be significant.