In natural settings, hosts are often exposed to varying levels of pathogen, and within a population, there may be significant heterogeneity in the exposure dose and total number of exposures to a given pathogen [e.g. 19 ].
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In the literature
Discussion In this study, we developed a theory for size-dependent growth of intracellular structures and organelles to uncover the design principles for robust size regulation of intracellular structures in the noisy environment of the cell, where stochastic fluctuations may be significant.
Traffic and economic problems caused by the aging of the population and the shortage of public transportation may be significant reasons for restricted economic development. 5.4.
While needing confirmation, by allowing us to parse different developmental stages, our system suggests there may be significant differences between mice and humans in terms of the temporal expression of BA genes.
Discussion En bloc resection remains the real curative treatment of Schwannomas, ensuring unlimited freedom from disease, although causing functional impairment which may be significant.
In fact, there may be significant seasonal variation in the wildfire related impact on land surface temperature, with large changes during the summer and small changes during the winter [ 10 ].
This change in density with activating Fab may be significant because the model in the literature for the monomeric state of E-cadherin has the Trp2 forming an intramolecular bond, filling the hydrophobic pocket in its own subunit, and the extrusion of the Trp2 leads to the intermolecular strand-swap dimer that underlies adhesive bond formation.
Lastly, it should be noted that a POE may be significant with both paternal and maternal transmissions separately and there may still be a significant difference between them, if the association trends are discordant across both parental transmissions (i.e., the same allele may increase the score significantly when inherited from the mother but decrease it significantly when inherited from the father, or vice versa).
Home-range sizes of order 1–10 km cited for many California rockfish species [26] , [35] , for example, may be significant in terms of their effects on persistence for reserves that are often the same order of magnitude in size [25] , particularly when the distribution and amount of harvest effort is not controlled.
In addition, there may be significant texture variations and noise in the background.
Alterations in this gene can disrupt proper protein folding and membrane localization, impairing its function as a transmembrane receptor, which may be significant in the context of cancer ( 23 , 24 ).
Microbial nutrient cycling observed in fast-flowing supraglacial streams [ 49 ] suggests that microbial processes may be significant in fast-flowing englacial conduits.
The time course of satellite cell population divergence between males and females suggests that androgens may be significant mediators of satellite cell number.
The authors determined that requiring a days’ supply greater than 7 days effectively removed many short-term prescriptions from being associated with distant CV events while recognizing that previous studies indicated that CV risk may be significant within the first 30 days. 6 , 11 , 33 NSAIDs were identified by national drug codes.
This may be significant in terms of the treatment of hypoxic regions of tumours (see below).
The differences in gene expression across these pathways may be significant contributors to the variation in photothermal sensitivity between the two varieties.
Cell damage from oxygen free radicals (OFR) is ubiquitous and may be significant in the expansion of tumor clones and the acquisition of malignant properties [ 135 ].
This may be significant in terms of increasing the use of traditional white grape varieties by farmers/producers since high antioxidant/phenolic concentrations were linked to disease resistance traits in plants and may facilitate the development of marketing strategies focused on “added nutritional value” to increase consumer demand [ 11 , 36 ].
Research on this is limited but it may be significant that of the 4 superinfected patients identified, 2 were diagnosed early after infection and superinfection was demonstrated respectively 4 and 5 months after diagnosis.
The findings suggest that hypercoiling and abnormal cord length may be significant risk factors for UAT, warranting further investigation into their pathophysiological mechanisms and clinical implications. umbilical artery thrombosis single umbilical artery fetal growth restriction prenatal ultrasound hypercoiling abnormal cord length The author(s) declare that financial support was received for the research and/or publication of this article.
On the one hand, both may be significant to the constellation of complaints (and thus warrant treatment), and on the other hand, either one could be of less importance, or even be irrelevant.
9 Another strategy to change the magnetic structure is to replace Bi with Mg 2+ ions because the super exchange interaction between localized Mg 2p and Fe 3d electrons may be significant in the perovskite-like structure.
For example, previous studies have found that narrative impairment and low psychological resilience may be significant predictors of increased suicidal ideation, while certain religious beliefs may be protective factors for suicidal ideation formation 11 , 12 .
Given that most SCN neurons are GABAergic, the activities of two of the receptor genes Gabr b1 [7dpi↓] and Gabr d [7dpi↑] may be significant.
Thus, this study suggests that caregiving stress among female family caregivers may be significant enough to lead to a functional decline of the kidneys, as well as high blood pressure.