Clinicians and patients who decide to use targeted therapies in the metastatic setting should understand that treatment-related toxicities may be significant and a detriment to quality of life.
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In the literature
A large proportion of young stock mortalities occur within the first seven days of life, particularly in small ruminants, so such unrecorded omissions may be significant.
However, for many people who face such dilemmas in their public life, the consequences of silence may be significant enough to outweigh the epistemic reasons for silence.
subtilis , suggesting there may be significant differences in the mechanisms involved in translational initiation and regulation in mycoplasmas.
Abnormal myocardial energetics may be significant in cardiac pathophysiology [ 49 ], so variation here may logically be associated with LVH.
In a number of biological application areas, including tissue engineering and thermoregulation, natural convection may be significant.
The G-pro- tein-coupled receptors, which have impor- tant roles in humans, may be significant in triggering barnacle settlement.
Overall, these findings suggest that while HRV changes may be significant for Focus sessions, they do not explain the stress-reduction effects of Motivation-based interventions.
Finally, given that onset symptoms are usually syncope, or sudden cardiac arrest, the clinical utility of this measure may be significant to clinicians.
3 A ) and may be significant pharmacologically, but the mechanistic basis of this difference is unclear.
Additionally, it pinpoints the potential features that may be significant for double-strand breaks leading to chromosomal rearrangements.
Additionally, there may be significant differences in the duration and intensity of 18 F-FDG uptake depending on the fracture site and severity [ 19 ].
POLICIES REGARDING TRACHEOSTOMY With 9.8% to 15.2% of COVID patients requiring prolonged invasive mechanical ventilation, 4 , 7 , 8 , 9 , 10 it is of critical importance to establish early guidelines with respect to performing elective tracheostomy, as risks to the healthcare team may be significant. 11 , 12 Our departmental policies regarding tracheostomy are consistent with those of the New York Head and Neck Society (NYHNS), which recently released comprehensive guidelines on the matter. 13 When feasible, we generally advocate delaying elective tracheostomy until 21 days after s
While it is likely that the ambulatory hospitalizations might capture some of the emergency department visits, there may be significant HCRU by patients with SCD or TDT not captured.
Introduction Although there are a few analgesic choices after a kidney transplant operation, there may be significant postoperative discomfort [ 1 ].
Auxin, sugars and other hormones such as cytokinins, ethylene, abscisic acid (ABA), giberellins and strigolactones are implicated in phosphate-induced determination of RSA so genes involved in these pathways may be significant candidates [ 103 , 146 , 147 ].
However, there may be significant concern should a client want to use their cells in the pursuit of a risky or unproven regenerative medicine therapy.
Comparing the APAC-SZL group to the APAC-ZL group, sitting ACD[(1.75 ±0.19) mm vs (2.19 ±0.24) mm], supine ACD[(1.27± 0.12) mm vs (1.62± 0.17) mm], LT[(5.41 ±0.38) mm vs (5.08 ±0.34) mm] reached statistical significance (P=0.000, P=0.000, P=0.006). Compared with the other two groups, the values of ACD and LT in the APAC-SZL group were significantly different, which indicated that the zonula may be significant abnormal in APAC patients with a thicker LT and a shallower ACD.
However, unless his GP mentions the duration of the symptoms or that John has a large rectal mass, or iron deficiency anaemia, or has inexplicably lost several kilograms in weight over the past four weeks, John may well be allocated an appointment in several months time by which time there may be significant progression of his underlying malignancy.
It is possible that the eight local names given by fishers for fishes no longer caught that could not be found in field guides may be significant in this regard.
( 2015 ) proposed that motor co-ordination, speed, and aerobic endurance may be important in soccer prior to and during one's age at peak height velocity, and explosive power may be significant after the age at peak height velocity.
Owing to bioaccumulation, the level of cadmium in the tissues of fish, especially those at the top of the trophic chain, may be significant and endanger the health and effective spawning success of the species due to impairment of the reproductive capacity.
In particular, the presence of MB and TMB from later sampling times, where plastic degradation occurred, suggests that there may be significant differences in some metabolic activities compared to the same samples after 3 months of incubation.
28 , 29 However, the risk of venous thromboembolism may be significant even in patients with focal segmental glomerulosclerosis, 30 – 32 and the low rate of reported adverse events with therapeutic anticoagulation as well as our patient’s markedly decreased serum Alb levels encouraged us to pursue pharmacological prophylaxis as practiced in the ordinary clinical setti
Experimental evidence indicates that despite natural radiation background is presently extremely small nevertheless it may be significant enough for living organisms to sense it and respond to it, keeping memory of this continuous exposure.