“may be significant”

Firstly, incorrect categorization of green tea may be a key factor leading to inconsistent results, as there may be significant differences in the observed cohort, including factors such as concentration, brewing time, dose, and even the type of green tea.

However, a large fraction, if not a majority, of actionable cancer DNA alterations reported to date were done so using short-read technologies and are therefore are single-base mutations [ 13 ], and in tumor tissue samples, there may be significant cancer heterogeneity and/or low tumor fraction.

Therefore, although T-CHI may be perceived as a relatively “mild” illness, the long-term impact of neuroglycopenia causing adverse neurodevelopment may be significant and under-diagnosed.

Monocins are bacteriocins produced by the host that may be significant in establishing dominant strains in ecological niches, as they target closely related species, but remain inactive against the producing strain 53 .

This is because the effects of constraints may be a criterion for determining how much the performance of the material is affected, and the effects may be significant at low temperatures.

However, studies have suggested that the survival benefit of R0 resection over R1 resection may be significant only in T1b, T2, and certain T3 stage tumors [ 17 , 44 ].

In this context, the transition from heptameric to hexameric rings may be significant during the loading of Rep proteins onto dsDNA.

These pathways are highly associated with the regulation of angiogenesis and anti-inflammation systems, which may be significant pathways for the alleviation of the symptoms of HLP.

In addition, the urinary ATP reflects the urinary microbial biomass directly post void and there may be significant variation in the urinary biomass at the time of culture secondary to transportation and processing delay.

Given that in most pre-clinical studies, it is common practice to associate the total count in intensity being proportional to the total amount of activity (for example total number of tagged cells), a small variation in animal positioning can lead to a large variation in detected activity which may be significant.

Because zebrafish experience aging related phenomena, it may be significant to develop a consensus of best practices regarding age at MPTP injection.

Within the San Juan River sediments, Pb contribution from upstream mining is detectable and constitutes a significant fraction of the Pb contained within bed sediments, although Pb concentrations are below aquatic risk levels. Broadly consistent source attribution results observed over several decades and the asymptotic concentration trend with distance from the headwaters region suggest that the Pb background may be significant and variable in space.

Given that physiotherapy has a strong influence on the recovery from rotator cuff disorders there may be significant effects.

CRC has a high degree of heterogeneity and there may be significant differences in gene expression patterns between different individuals, which may lead to large differences in the performance of the model in different patients.

We considered two possibilities: (i) DASDC corrects potential differences between simulated and real genomic features, thereby reducing the impact of distributional differences and obtaining more accurate classification results, and (ii) there may be significant differences in characteristics between the simulated genome and the real genomes, with LCT genes undergoing strong natural selection that could exhibit features similar to those observed during a hard sweep in simulated genome data.

However, understanding its implications in non-cancer contexts (such as inflammation and hypoxic pulmonary hypertension) may be significant ( 127 , 128 ).

Under this mechanism, the time between proliferation events may be significant.

More attention is needed for soil CO 2 emissions in the non-growing season, not just the growing season, because the former may be significant for the annual carbon budget 32 , 33 .

However, analysis of sequential use has revealed that there may be significant additive potential if not synergistic, in enhancing the immune response to cancer.

Sex and gender differences in stress and susceptibility may be significant.

Because most WNV infections are asymptomatic or mild, many human infections may not be recognized, and there may be significant underreporting of milder symptomatic cases [ 133 , 279 ]. 10.

It is tempting to speculate whether failure of CX 3 CR1 deficient cells to tubulate, or initiate differentiation into mural smooth muscle-like cells or impairment of extracellular matrix production may be significant contributors to increased microvessel porosity to blood and solutes in vivo thus providing a mechanism underlying the leaky MV phenotype.

These promoter indels increase risk of upper aerodigestive tract cancers (UATC) more than twofold suggesting that BRM downregulation may be significant for development and progression of GI cancers [ 77 ].

Depending on the size of the macrocycle, the internal functionality may be significant in directing the formation of the macrocycle, or may be optimised for metal coordination or other guest recognition.

In contrast, in species such as cats, which have lower heart rates than rabbits, even small differences may be significant.