“may be significant”

Given that the Developmental Origins of Health and Disease field of research is a relatively young research area, many early life factors that may be significant in relation to cognitive decline and dementia disorders have not yet been investigated as such.

This may be significant because the WBP2NL knockout was only performed in mice [ 24 ], thus perhaps WBP2 is only able to compensate for a lack of WBP2NL in mice and other murids.

Our results indicate that the NAD-associated redox homeostasis may be significant with regard to pollen desiccation susceptibility.

Attitudes to mental disorder and help-seeking are based on laypeople’s concepts of disorder, not directly on those held by professionals, and the disparities suggested by our findings may be significant.

These are mostly involved in post-translational modification, carbohydrate metabolism, inorganic ion transport, energy production, and enzymes includesgalactosidase, catalase-peroxidase, and chitinase which may be significant in the pathogenesis contribute to the high virulence of the wilt pathogen ( Sun et al., 2014 ). deSain and Rep (2015) have reviewed the proteins secreted by pathogens, such as wilt fungus FOL during colonization to establish aeffective pathogen-host communication.

Importantly, these dynamic conformational transitions may be significant for regulating protein-protein and protein-DNA interactions mediated by PCNA during DNA replication and repair.

In considering the discrepant outcomes of these studies, the critical question to be answered is ‐ what provides protection? For example, the implications of using a different adjuvant may be significant: a non‐human primate (NHP) study examined MF59 versus aluminium hydroxide.

While clinically inconsequential in healthy children, it may be significant in vulnerable populations.

The extent to which these spaces are or are not affected by the new road may be significant in terms of local experiences of a severance effect, and this may affect ‘acceptance’ of the new infrastructure; however further research is needed to investigate this.

This highly variable pattern of results suggests that there may be significant measurement error and/or that the cognitive processes engaged during many tasks change with repeated performance (e.g., due to learning).

These findings may be significant in understanding the development of OA after ACLR.

It is conceivable that larger numbers of appendicoliths and larger-sized appendicoliths found on CT may increase the likelihood of acute appendicitis and that these findings may be significant enough to support a recommendation of an elective appendectomy in asymptomatic patients.

In contrast, sargramostim, a recombinant human GM-CSF is under investigation, to improve the immune response by recruiting neutrophils, dendritic cells and macrophages to fight the virus and to repair tissue damage ( Table 1 ), although there may be significant risks including neurotoxicity ( 103 ).

These results implicated that ING proteins may be significant modulators of p53 function.

Despite a much lower overall sample size, our study suggests there may be significant differences in sudden death risk factors between Black and White cohorts with HCM.

However, despite their intermediate-risk karyotype, both patients with EIF4A1 rearrangements exhibited primary drug resistance, suggesting that alterations in this gene may be significant risk factors.

This may be significant given that the E.histolytica genome is highly A + T rich.

This may be significant because neurogenesis after BBBD over a relatively large volume of the brain has been proposed to occur due to changes in the extracellular matrix regulating perineuronal nets, as well as ERK expression and signaling ( Figure 7 ).

This situation may be significant for firms operating in digital-related industries (i.e., the beneficial industry group), because remote work is likely to persist even after the pandemic recedes.

Its clinical implications may be significant, allowing customized treatment plans, enhancing prognostic evaluations, and directing the creation of targeted therapeutic agents.

32 The difference in mean cIMT between children with FH and unaffected siblings may be significant as early as age 7 years ( Figure 3 A ). 33 Similar findings were observed for mean femoral artery IMT. 34 Coronary calcification is present in ∼25% of 11–23 year olds with phenotypic HeFH, and especially in the aorta in most adolescents with HoFH, although coronary and aortic calcium score is rarel

There are no reported genotype/phenotype correlations in BTHS and it is increasingly recognized that there may be significant intrafamilial phenotypic variability [Ronvelia et al., 2012 ].

Although there are no specific data on the proportion of pregnant women in crisis with unmet medical needs, a survey by the Korean Unwed Mothers Families Association [ 14 ] suggests that this proportion may be significant.

Therefore, the gene REM22 may be significant for the carpel structures development of inap CMS.

Nevertheless, there is much work to do in identifying optimal strains and using meta-analysis to prove the effect size of the disease (which in some cases may be significant, but only minor).