“may be significant”

Although the increased sensitivity of morphine-treated rats to the antinociceptive effect of diclofenac may be significant, the exact mechanism could not be determined.

Theoretical framework In a review of this nature, it is expected that there may be significant variations in the nature of the interventions to be studied.

However, the fact that parents with lower education are less likely to seek help may be significant, as may be the location of the outpatient clinic from which data in the large town were analyzed.

Previous studies have noted that points with a sensitivity of less than 20 dB have less effect on the rate of visual field progression.[ 9 ] During the initial stages of glaucoma, the rate of progression correlates with glaucoma severity; however, for severe glaucoma, the rate of progression is low.[ 10 ] Due to the reduction in variability, even a change <5 dB may be significant for eyes with advanced glaucoma.[ 11 ] Point-wise linear regression (PLR) is analyzed based on individual threshold, total, and pattern deviation values.[ 12 ] PLR analyzes focal changes and underestimates diffuse change.

On the other hand, there may be significant heterogeneity and methodological flaws in the previous meta-analyses.

Nevertheless, this analysis strongly suggests that the effects of nonlinear interactions may be significant in the dynamics of plaque formation and regression.

Less well documented are the costs of early-stage CKD which may be significant given increasing prevalence [ 3 ].

Military requirements have often driven progress in civilian trauma medicine and these developments may be significant in understanding and developing UAV potential in civilian evacuation pre-hospital practice.

The following substances may be significant to the molecular basis of SIRS: Haemoxygenase-1 (HO-1) - implicated in the defensive response to oxidative stress; it has been found to attenuate TNFα mRNA synthesis and plasma TNFá levels, reduce lung injury and improves organ perfusion [ 33 ].

However, at higher percentages of doubly transformed cells this effect may be significant ( S1 Fig .) and controls must be run to minimize artifacts [ 36 ].

arabiensis which may be significant for certain studies, such as those examining the spread of resistance genes in mosquito populations.

Our findings support existing literature that having more prior mammograms 59 , 62 , 64–66 and higher levels of future screening intent and self-efficacy 65 , 67 may be significant drivers of adherence to subsequent mammography.

This may be significant because the Notch pathway plays a major role during developmental angiogenesis, including tip/stalk cell specification and endothelial cell sprouting ( Roca and Adams, 2007 ; Phng and Gerhardt, 2009 ).

Furthermore, considering that SA has the potential to improve plant resistance to challenging environmental conditions, its application may be significant for sustainable agriculture under such conditions [ 38 ]. 3.

In this connection, it may be significant that the solubility in serum of finely divided metallic nickel, produced by the chemical reduction of NiCl2, is increased in the presence of oxygen, whereas that of the coarser, commercial preparation is not.

The mere presence of a contractile response after incubating arteries with four different ( S )-epimers indicates that their presence in human diets and animal feed may be significant and should be considered in analytical and food safety assessments.

Since the saturated standard cell emf stability depends on an electrochemical equilibrium within the cell, small charging or discharging currents that are present at the input of the DVM will produce changes in the cell emf that may be significant.

16 months with ibrutinib), which may be significant for future fixed duration strategies [ 21 ].

This may be significant in schizophrenia, as cognitive deficits respond poorly to conventional antipsychotic pharmacotherapy and the retinoid system may act as a modifiable enhancer of cognitive performance.

However, longer loops may be significant if they are stable, long-lived, or have a larger lifetimes than the timescale ( τ ) in our model.

Simple synthesis steps and good reproducibility of this method are its main characteristics; however, particle agglomeration may be significant.

pneumoniae infection is related to thrombotic events is not fully understood, but there is evidence that the interplay between the coagulation pathways and the complement cascade may be significant.

9) The differences in gene expression reported in Figure 6C may be significant because of the high number of genes included in the comparison, but these differences are very small and not likely to be biologically important.

In contrast, the mean of the upper group (" upper ploidy group ") is close to the normal tetraploid epithelial value (220), the range is somewhat wider, and there are many hypotetraploid cases as well as some in the hexaploid region (mean = 223 ? 43; coefficient of variation = 20 per cent). Although the numbers are fewer, the corpus cases present differences from the cervix cases which may be significant: there are relatively fewer tetraploid tumours and none in the hypertetraploid-hexaploid region; on the other hand, there are ri. 4 ri. q t t4. c c ?2 FIa. 1.-Basic DNA value of 122 untreated cervical carcinomata (above), and 30 untreated corpus carcinomata (below). 2 hypodiploid tumours.

In addition, the morphological features of the SK-MEL-28 cells showed a reduction in cell size and the rounding up of cells in the presence of IL-4 (25 ng/ml)–activated NK-92MI cells when compared with treatment with either IL-4 (25 ng/ml) or NK-92MI cells alone ( Figure 6 B ); however, NK cell and IL-4 inhibitory was abolished in the presence of TNF-α may be significant in the NK cell mediating IL-4 cancer cell growth inhibitory effect.