“may be significant”

Although the time efficiency gains are modest in absolute time (minutes), may be significant at scale based on the number of patients per year.

Strategies are required to strictly avoid re-exposure of patients to drugs which carry an increased risk of inducing a dangerous reaction, whilst minimising the avoidance of drugs which are of minimal risk or allowing the use of low-risk drugs where the benefits may be significant.

In the elderly population, nonspecific symptoms like weakness and exhaustion should not be disregarded as they may be significant indicators that anemia is present in these individuals.

While acute toxicity thresholds are comparable between all species tested, the ability to conduct toxicity assays at the same native salinity as the mesopelagic crustaceans may be significant in terms of greater compositional similarity in exposure media.

This is particularly important as the normalized dose-response gradient for tumors and OARs is steep [ 7 ] and therefore, the risk of under- or over-dosing may be significant.

The behavior of visco-elastic materials under enormous deformations that may be significant in vivo is difficult to investigate using computer methods because of the complexity involved.

It may be significant that HRP internalized from the basolateral surface appeared in similar apical structures in studies using isolated perfused proximal tubules (Nielsen et al., 1985).

There may be significant differences in genetic background, environmental factors (such as diet, lifestyle), and disease characteristics between the two populations, which may lead to inconsistent effects of the instrumental variables (genetic variants) in the MR analysis, thereby affecting the accuracy of causal inference.

Another explanation is the increase in the use of automobile transport, factory machines, other equipment, and gadgets, which may be significant contributing factors. 4.1.2.2.

It may be significant that ME7‐associated increases in IBA‐1, cathepsin D, and CD68 expression in white matter (cc and internal capsule) were mitigated in IFNAR1 −/− mice.

28 We have chosen to consider both acute and chronic forms of HRF together as the duration of ‘chronic’ HRF can be variable, and there may be significant overlap in causes.

Our findings suggest that disturbance in venous return and the associated altered oxygen may be significant changes in the retinal blood flow dynamics in eyes with SRF.

Compassion fatigue, which can result from providing empathetic care and seeing clients continue to suffer [ 79 ], and burnout, from prolonged work stress, may be significant factors impacting emergency responders treating overdose cases [ 80 ].

A limitation of the current study is the relatively small sample size; with a larger sample, the association between 6MWT distance and symmetry ratio and CMSA scores may be significant.

Our findings support the hypothesis that topiramate applied before HS can protect some neocortical synapses via the vascular factor by enhancing blood–brain barrier components and improving the blood supply of gray matter in the temporal lobe, which may be significant in febrile seizure-prevention in children.

Our finding that PCM1 is required for GBM ciliogenesis may be significant if GBM cilia serve as venues for promoting tumorigenesis, as has been observed in other cancer types (e.g., medulloblastoma, basal cell carcinoma, choroid plexus tumors) [53] , [54] , [55] .

This may be significant for better understanding the conditions under which speleothems develop, the impact of climate change and increasing visitor numbers, the preservation of cultural relicts, and the need to maintain the cave environment for fauna and flora therein.

For one, study attrition may be significant and may occur for several reasons.

In the case where the ID segments folds upon binding, ΔG strain may be significant.

Bioinformatics analysis suggests that the HIF-1, Jak-STAT, and TGFβ signaling pathways may be significant routes through which C3AR1 participates in preeclampsia.

These mechanisms may be significant in the prevention of POCD following general anesthesia.

Symptomatic uncomplicated cystitis (women): Counts as low as ≥10 2 –10 3 CFU/mL may be significant (e.g., for E. coli , Staphylococcus saprophyticus ) when clinically concordant. 3.

Device availability is currently restricted, and initial capital investment may be significant.

Benzodiazepine and benzodiazepine-like drugs Benzodiazepines are widely used in clinical anesthesiology as anxiolytics, amnestics, and sedative–hypnotics.[ 49 ] They are less commonly used as anesthetic induction agents because at the doses typically required to produce anesthesia, cardiovascular depression may be significant and recovery prolonged.[ 9 ] Among anesthesiologists, midazolam is the most commonly used benzodiazepine because it has a relatively short duration of action.

However, there may be significant differences in the data quantity and wind intensity between different periods.