Barely Significant
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“may be significant”

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In the literature

We only find significant enrichment in three of the ten control cell types, including embryonic stem cells (VSE, Bonferroni-corrected p ≤ 2.36 × 10 −4 ), cervical carcinoma cells (VSE, Bonferroni-corrected p ≤ 3.38 × 10 −3 ), and mesoderm leukemia cells (VSE, Bonferroni-corrected p ≤ 2.87 × 10 −3 ), indicating that there may be significant sharing of cis-trQTL-related chromatin markers between these cell types and LCLs (Fig. 5f ; samples H1hescPk-1, Helas3Ifna4hPk-1, and K562Pk-1).
There is no doubt that a glomerular filtration rate (GFR) above 90 ml/min defines a normal renal function; “good” renal function is usually defined as a GFR above 60 ml/min, even if, at least according to the Italian experience, there may be significant differences between patients with GFR ≥ 90 ml/min and those with 60–90 ml/min of GFR [ 56 ].
In this regard, a review of research on friendship in digital spaces clearly reported that the core components (such as validation, intimacy, or conflict resolution) contributing to perceived friendship quality identified for the offline context (Parker & Asher, 1993 ) may be significant also when friends interact on social media (Yau & Reich, 2018 ).
44 In the context of high energetic demand or high oxidative stress, mitochondria may be significant in regulating the quality of aging or pathological mitochondria, as well as in reproducing robust mitochondria to maintain mitochondrial homeostasis and meet the consumptive energy requirements. 23 On the other hand, activation of Cdc42 also acts as a binding partner of NDRG1, which regulates mitochondrial fission during fasting, and as the key regulator of mitochondrial polarity, which is crucial for cellular respiration. 18 , 45 Thus, Cdc42 might regulate mitochondria directly or indirectly through ERK1/2 signaling in ameloblasts.