We believe that the low number of recruited patients and possibly differences in age between the patients in the intervention and the control group may be significant causes for this.
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Therefore, motor phenotypes, such as RMMA and NSMA, may be significant confounding factors for interpreting the pathophysiological relationship between OSA and SB.
For example, a variable may not be important when we fit one model to all of the data, but it may be significant in some or all clusters when we use the CLR technique.
As experience and this review have demonstrated, these costs, which include both direct and indirect economic costs, may be significant.
Our study likely underestimates the unaccounted costs associated with OPAT; however, costs incurred may be significant and differ between care models.
Mitral regurgitation is secondary to the left-sided dilation and may be significant.
USCs have the potential for myoblast differentiation and may be significant candidates for skeletal muscle regeneration, as indicated by their expression of specific skeletal muscle lineage transcripts and protein markers, such as myf5, myoD, and myosin ( Chen et al., 2017 ).
Although the increase in both shear and effective stresses because of increased MIB (between displacement levels of 0, 4, 8, 12, and 16 cm) is small as a percentage of baseline values, the consequences may be significant.
The two families used in this study were derived from a long-term selection, and there may be significant differences in other phenotypic traits besides the disease resistance trait, such as fatty acid metabolism, skin color variations, thermal acclimation, and sex ratio.
For a given undercut length U /2, the linear relation between L and w for CJs is increased by the total contraction u of both anchor overhangs, as indicated in Figure 6c , which may be significant in case of large undercuts.
It was also found that despite the structural similarity among various flavonols, there may be significant differences in their anti-inflammatory effects [ 73 ]. 5.1.
Based on these data, therapy aimed at upregulating BCL6 expression may be significant in treating HFD-induced NAFLD.
It is possible that the nature of the tumor-initiating oncogenic event may be significant in determining the genomic stability of the tumor and this may have implications for tumor behavior and prognosis or somatic inactivation of the putative susceptibility gene, located at 19p13.2, has occurred through the other mechanisms, such as microdeletions, point mutation, or promoter hyper-methylation and interact with this region.
There may be significant differences in vaccine immune response depending on whether the person is previously infected with SARS-CoV-2, the time elapsed after recovery from infection, and the interval between vaccinations.
Rarely, the patient admits to unorthodox self-treatment that may be significant (e.g., peroxide irrigation, overzealous nasal cleaning).
The fluctuations in perioperative parameters among esophageal cancer patients may be significant; however, this study was unable to specify how these dynamic changes affect intraoperative hypothermia, and it excluded the population with preoperative temperatures below 36.0°C.
This estimated surgical procedure need by regions and not by countries can lead to bias, since there may be significant differences between countries within a same region.
However, there may be significant hurdles in maintaining surface expression on target cells as it is not known to what degree exosome endocytosis will occur in different tumor models.
The ability of intimin to also bind β–integrins may be significant in this regard ( Phillips and Frankel, 2000 ).
While this may reflect reluctance among minorities to engage in such activities, in addition there may be significant access barriers to these types of services.
Race/ethnicity and store characteristics may be significant factors in participants’ brand choices.
It may be significant that the E. blochii diet was found to consist of about 93% teleost fishes, apparently of the family Clupeidae 25 , whereas other hammerhead species feed predominantly on stingrays, crabs, and other bottom-dwelling organisms 26 .
Renal EVNP has not been reported in the United States, but its potential to expand the donor pool may be significant, considering the large number of potentially transplantable organs currently being discarded.
This local risk signature may be significant for assessing and mitigating risk in the future.
This highlights the need for a control group in similar studies, as the control group may have also had declining physical activity, but the difference in the two groups may be significant.