“may be significant”

While the relative proportions of these mechanisms are unknown, there is evidence that both mechanisms may be significant.

Importantly, there may be significant underestimation of the cerebral involvement as transient ischemic attacks affecting one or more cranial nerves, large vessel involvement, and a cerebral vessel aneurysm have also been described [ 1 , 2 ].

In contrast to data from Brazil and the United States, which showed higher rates of adherence in pregnant women, data from sub-Saharan Africa has indicated that there may be significant adherence issues in pregnant women initiating antiretrovirals [ 25 , 26 ].

Notice that the voltage drop across R s may be significant when R s (typically ∼ 10 Ω ) is not negligible compared to the overall resistance due to the quenching resistors ( R q ∼ 100 k Ω ) of thousands of pixels in parallel. 2.2.

The hub genes may be significant if the expression patterns were the same in both the external data set and the training data set.

Whilst the CASC may be reliable (although as yet unproven), there may be significant problems related to validity, authenticity and acceptability, including in its costs.

Differences may be a result of vaccine formulation or protocol used, the biological properties and characteristics of the agent and host, or the involvement of newly identified or emerging pathogens ( Erles et al., 2004 , Priestnall et al., 2014 ) Whilst these first two points fall beyond the scope of this study, in examining four of the most important emerging CIRD pathogens it is clear their role in CIRD may be significant for both kennelled and pet dogs.

This study may be significant for clarifying the therapeutic mechanism of SLT on stroke and for searching effective drugs for stroke remedy.

There may be significant advancements in reducing the energy demand or increasing the membranes lifetime.

These changes may be significant as horses are heavily dependent upon their microbial communities for nutrient absorption.

Nitrite binding and turnover is a dynamic activity and the flexibility of Ile257 observed here may be significant in this process by imposing the steric constraints required for optimizing the nitrite-binding geometry.

The locations in CA of the mutations that sensitize SIVmac239 to papionin and cercopithecin TRIM5α-mediated restriction may be significant.

However, there may be significant clinical variation in how germline vs somatic mutations and alterations behave in response to therapy, exemplified by improved response to carboplatin vs docetaxel observed in patients with germline BRCA1 mutations but not in those with BRCA1 methylation or low mRNA expression [ 55 ].

Where there are no strategies to identify mothers with sputum smear-negative TB, there may be significant delays in diagnosis and extended exposure of young children to risk of infection [ 25 , 26 ].

The proliferation of histiocytes can be a paraneoplastic response and there may be significant morbidity and mortality because of joint involvement and malignancy.

Recently, certain species of wild plants and fungi have received a great deal of attention in Mediterranean countries, and at the same time, the consumption of lesser-known plants that may be significant for prevention of illnesses has been documented.

Furthermore, there may be significant variations in drought tolerance among the cultivars [ 42 ].

The results presented here show that the class Gammaproteobacteria may be significant at higher temperatures.

Thus, if FB recruitment can be used to build credibility and positive expectations of intervention, then their potential for recruitment may be significant. 4.1 Limitations Several limitations of this study should be acknowledged.

The remarkable prevalence of PIK3CA and KRAS mutations in DNA from normal tissues suggests that there may be significant opportunities for cancer prevention.

The fact that the PFC matures last and that myelination is not complete until late adolescence may be significant, as the timing coincides with the typical onset of symptoms in schizophrenia.

The consequences of co-induction of these two particular enzymes may be significant.

The impact may be significant in resource-rich countries but may provide even further impact in resource-restricted countries.

The implications of these results may be significant in not only designing clinical trials, but also in managing patients.

In this connection, it may be significant that the same occurs for the body of the larva, which gradually increases in length from around 5 mm at hatching up to 180 mm before metamorphosis, though there is an astonishing variation in growth rates (reviewed in Hardisty and Potter, 1971 ).