“may be significant”

Despite this identity at the 16S rRNA level, there may be significant differences both at the gene content level, as well as in the identity between shared genes.

The occurrence of this GC-rich motif in the genome is low ( Table S2 ), suggesting that its presence in upstream sequences may be significant for transcriptional regulation.

However, especially for nucleotides between the shift site and a recognized 3′ stimulator, ‘spacer’ nt identity has to be treated carefully since it may be significant ( 405 ).

This suggests that in vivo increases in Paneth cell number may be modest, yet their biological effect may be significant, and therefore a particularly sensitive method of quantification is preferable.

Our study suggests that there may be significant longitudinal neurometabolic changes in the pediatric population leading to differences detectable beyond the acute time point, and we add to previous 1 H MRS studies of pediatric concussion by examining the chronic time point at 1 year post-concussion.

However, there may be significant efforts and advanced models developed for other languages that were not included in this review, representing a limitation in scope.

Although a small number of EAS studies have delved into EI [ 14 , 112 ], there may be significant merit in exploring further the synergy that may exist between the two, including possible ways in which this may be enriched through careful inclusion of EI in programme development.

Hence, this weak and controllable mechanical property of the buckled CNTs may be significant for designing the restorable CNT-based devices to perform overloading tasks.

There may be significant variations in pain perception, skin recovery, and subjective experiences among different patients, potentially affecting the accuracy of the results.

This current result may be significant because the synchrony of decreasing precipitation and rising temperature may lead to high potential evapotranspiration and low water availability, not only in the Northern Chinese steppe ecosystem ( Wang and Gao, 2003 ; Cheng et al. , 2006 ) but also in many of the semi-arid regions of the world, such as the Patagonian region of Argentina ( Paruelo and Sala, 1995 ), the western European grassland ( De Boeck et al. , 2007 ), and the Chihuahuan Desert of the USA ( Patrick et al. , 2007 ).

While respiration- and manipulation-induced vertebral motion is typically small, there may be significant variability in magnitude, particularly with spinal region and ventilator parameters.

A problem with this is that there may be significant variation in response between individuals, not least owing to differences in olfactory sensitivity but also dependent on aspects of emotional state, such as individuals with social anxiety responding more strongly to anxious odours (Pause et al., 2009 ).

We found that evidence for individual-level risk factors may be significant in some countries, and null or opposite in others.

Previous studies showed that there may be significant variation across the country by region or state.

In this context, it may be significant that a CHH methyltransferase (Zm00004b000077 in W22; Zm00001d027329 in B73) is among the genes with elevated messenger RNA and sRNA levels in sickly plants ( Figure 8A and Figure S16A).

This case report demonstrates that inadequate consideration of patient distress and the repetition of consultations and investigations may be significant risk factors for anxiety.

The most challenging aspect of IHA, from regulatory and good practice perspectives, is the IHA(B) subcategory, in which there is little or no evidence base to justify the activity, and in which there may be significant financial and social costs.

This high percentage of MDR isolates indicates that cow’s milk and beef may be significant sources of MDR Salmonella infections, which is a serious public health concern.

Since ectopic transcription factor activities may be significant ( Figure 2A , model 4; and Supplemental Table 2 ), we tested whether the ectopic activity at 414 genes versus normal GATA2 activity was detected with P values from 0.01 to 0.1.

Accordingly, there may be significant clinically relevant data missed through unsupervised reduction of factors.

34 , 35 We suspect that concentrations of condensed and/or organic P may be significant in influent and in effluent from some technologies with novel solid/liquid separation or solids processing methods.

12 Regional variations in prehospital delay may be significant, and identifying the factors associated with delayed hospital arrival may uncover potential intervention targets for decreasing prehospital delays and enhancing access to time-critical reperfusion therapy.

Thus, a shallower typologization risks missing regional distinctions that may be significant to defining areal distributions.

The discovery that the vWFA of HC1 shares high structural similarity with vWFA domains of TEM8 and CMG2 may be significant given that these proteins are known to be functional receptors for the anthrax toxin ( 37 ), especially because IαI has been shown to protect against anthrax intoxication ( 54 , 55 ).

The use of a preliminary factorial design to elucidate which factors may be significant or not when assayed within the physiological ranges, simplifies the DOE used in the RSM.