“may be significant”

The effect of the scarring may be notable and the functional, social and emotional impact on the patient’s quality of life may be significant [ 4 , 5 ].

However, in some cases, this increase may be significant.

With lack of evidence follows a lack of regulations from boards of nursing, and there may be significant inconsistencies in clinical competency in nursing programs throughout the United States ( Bradley et al., 2019 ).

How circular ruffle formation could trigger increased PIP3 production within it is not known, but it may be significant that the ruffle forms a diffusion barrier [ 23 ], which could trap and concentrate critical reactants.

However, related costs may be significant and equally relevant in similar contexts, and policy makers should take these into account when making decisions about the funding of the programs at hand.

This drug and, to a lesser degree, isoniazid induces the metabolism of tacrolimus via the induction of the cytochrome P450 pathway, and thus the incidence of graft rejection may be significant in solid organ transplantation recipients.

Although they account for a small proportion of cases of secondary hypertension, the associated morbidity may be significant if unrecognized or untreated [ 1 ].

BVMD is an autosomal dominant retinopathy with the following clinical characteristics: the accumulation of lipofuscin within and beneath the RPE, which presents as yellowish, vitelliform, or egg-yolk-like lesions in the macula.[ 4 ] In contrast, ARB is characterized by multifocal yellowish lipofuscin deposits, cystoid macular edema, and subretinal fluid.[ 5 ] BVMD and ARB are associated with central visual loss.[ 6 ] Identifying the genotype–phenotype correlations that are associated with BEST1 mutations may be significant to clarify their pathophysiological mechanism.

Emerging concepts suggest that factors beyond absolute weight, such as the qualitative characteristics of adipose tissue and the development of a systemic inflammatory state, may be significant determinants of cardiovascular disease (CVD).

In this context, there may be significant differences between male and female mice.

Looking at the C–N stretching frequency in the gauche and anti conformers, the difference in value (55 cm −1 ) may be significant; but, it should be noted that the modes in question are not perfectly parallel and are not pure stretching motions.

In this way, ScanFold-Scan and ScanFold-Fold can be used to detect both conserved and nonconserved elements, which may be significant for recently-evolved viral strains, for example.

Damaged or torn clothing may be significant and provide evidence of force. 17 Our findings show that some victims (20.8%) changed their clothing before being examined.

Therefore, our findings may be significant and applicable to the general population of CLWH in Cambodia.

For example, upper-bound estimates of parameter values can be used to determine whether particular impacts may be significant.

This is a reason to suspect that the influence of GDM on the course of PE may be significant, causing a shift in the imbalance between proangiogenic and antiangiogenic factors derived from the placenta.

There may be significant differences between rural and urban settings.

This suggests that the impact of elevated RAR on adverse outcomes is continuous, and long-term or persistent red blood cell-nutritional metabolic abnormalities may be significant factors maintaining a high-risk state.

‘...a diverse community of culturable bacteria contaminates unused paper towels...some of these bacterial strains may be toxin producers...This may be significant for some clinical and industrial settings as well as for immunocompromised individuals...’ (Gendron et al . 2012 ). ‘From a hygiene standpoint, paper towels are superior to air dryers’ (Huang et al . 2012 ). ‘These results suggest that air dryers may be unsuitable for use in healthcare settings as

Although the 2.4 NTU average daily median in our data sits below that value, the frequent high turbidity events may be significant stressors, particularly when they coincide with high temperatures over summer.

Such shifts may be significant, as they could influence how the protein engages with potential inhibitors.

Broader analysis indicates that it is likely that the range of transitory factors particular to adolescents’ lives, including education, work and relationships, mean that focusing solely on those with the lowest incomes is likely to neglect those for whom the impact may be significant and long-standing, such as those who have started work young and those who are single.

Through these mechanisms, hTERT plays an essential role in maintaining mitochondrial homeostasis, which may be significant in the context of cancer, neurodegenerative diseases, or infertility treatment [ 88 ]. hTERT contributes to drug resistance in cancer cells by protecting mitochondrial DNA and reducing oxidative stress, thereby promoting cell survival.

The possible reason may be significant operative damage to neural tissue or development of retethering.

Hybrid interviewing offers the flexibility to balance convenience and financial considerations, with the desire for in-person connection and evaluation; however, its limitations may be significant enough to preclude its use.